Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …

The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling
mechanism that regulates fundamental physiological and pathological processes. Wnt–β …

Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease. There is
uncertainty around the economic burden of NAFLD. We constructed a steady‐state …

Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …

Hepatitis B and C viruses are a global health problem causing acute and chronic infections
that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the …

Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …

Hepatocellular carcinoma (HCC) is a leading lethal malignancy worldwide. However, the
molecular mechanisms underlying liver carcinogenesis remain poorly understood. Over the …

Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and
one of the leading causes of cancer-related death worldwide. However, the molecular …

Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity
and mortality. One peculiar observation in cells infected with HBV (or with closely‑related …

The majority of the human genome is not translated into proteins but can be transcribed into
RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins …