Liquid biopsy based on cell-free DNA (cfDNA) enables non-invasive dynamic assessment of
disease status in patients with cancer, both in the early and advanced settings. The analysis …

Background: Alzheimer's (AD) and Parkinson's diseases (PD) show deposits of improperly
folded modified proteins. Protein expression mechanisms are involved since the early …

DNA methylation is a highly regulated process that has a critical role in human development
and homeostatic control of the cell. The number of genes affected by anomalous DNA …

Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

Peptides are privileged ligands for diverse biomacromolecules, including proteins; however,
their utility is often limited due to low membrane permeability and in-cell instability. Here, we …

Described as the 'single largest unmet need in cardiovascular medicine', heart failure with
preserved ejection fraction (HFpEF) remains an untreatable disease currently representing …

Pancreatic cancer (PC) is assumed to be an intimidating and deadly malignancy due to
being the leading cause of cancer-led mortality, predominantly affecting males of older age …

Objective Hepatocellular carcinoma (HCC) is the fastest-growing cause of cancer-related
mortality with chronic viral hepatitis and non-alcoholic steatohepatitis (NASH) as major …

Any alteration at the genetic or epigenetic level, may result in multiplex of diseases including
tumorigenesis which ultimately results in the cancer development. Restoration of the normal …

Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen,
conferring poor clinical outcome | Blood | American Society of Hematology Skip to Main Content …