Alteration of epigenetic modifications plays an important role in human cancer. Notably, the
dysregulation of histone post-translational modifications (PTMs) has been associated with …

In human beings, there is a∼ 16,569 bp circular mitochondrial DNA (mtDNA) encoding 22
tRNAs, 12S and 16S rRNAs, 13 polypeptides that constitute the central core of ETC/OxPhos …

Background Most children and adolescents infected with the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or develop a mild coronavirus …

Abstract Human mucin-1 (MUC1) has attracted considerable attention owing to its
overexpression in diverse malignancies. Here, for the rapid and efficient detection of MUC1 …

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition affecting
behavior and communication, presenting with extremely different clinical phenotypes and …

Hepatocellular carcinoma (HCC) is a major cancer burden worldwide with increasing
incidence in many developed countries. Super-enhancers (SEs) drive gene expressions …

Biomarkers for holistic animal welfare monitoring represent a considerable unmet need in
veterinary medicine. Epigenetic modifications, like DNA methylation, provide important …

Type 1 diabetes is a chronic autoimmune disease in which the destruction of pancreatic β
cells leads to hyperglycemia. The prevention of hyperglycemia is very important to avoid or …

DNA methylation at the CpG dinucleotide is considered a stable epigenetic mark due to its
presumed long-term inheritance through clonal expansion. Here, we perform high …

Environmental stressors are assessed through methods that quantify their impacts on a wide
range of metrics including species density, growth rates, reproduction, behaviour and …