Identifying genes whose expression is associated with schizophrenia (SCZ) risk by
transcriptome-wide association studies (TWAS) facilitates downstream experimental studies …

Objective: Posttraumatic stress disorder (PTSD) is a debilitating neuropsychiatric disease
that is highly comorbid with major depressive disorder (MDD) and bipolar disorder. The …

Ancestral differences in genomic variation affect the regulation of gene expression; however,
most gene expression studies have been limited to European ancestry samples or adjusted …

The immune system has long been hypothesized to play a role in schizophrenia
pathogenesis based on data from diverse disciplines. Recent reports of the identification of …

Objective: The shared risk factors and clinical features in schizophrenia and bipolar disorder
may be linked via mitochondrial dysfunction. However, the severity of mitochondrial …

Neuropsychiatric phenotypes have long been known to be influenced by heritable risk
factors, directly confirmed by the past decade of genetic studies that have revealed specific …

A role for immune processes in the pathogenesis of schizophrenia has been suggested by
genetic and epidemiological studies, as well as cross-sectional studies on blood and brain …

Quantitative trait locus (QTL) analyses of multiomic molecular traits, such as gene
transcription (eQTL), DNA methylation (mQTL) and histone modification (haQTL), have been …

Schizophrenia is routinely referred to as a neurodevelopmental disorder, but the role of
brain development in a disorder typically diagnosed during early adult life is enigmatic. The …

Schizophrenia (SZ) and bipolar disorder (BP) are highly heritable major psychiatric
disorders that share a substantial portion of genetic risk as well as their clinical …