Alternative splicing of schizophrenia risk genes, such as DRD2, GRM3, and DISC1, has
been extensively described. Nevertheless, the alternative splicing characteristics of the …

Despite strong evidence of heritability and growing discovery of genetic markers for major
mental illness, little is known about how gene expression in the brain differs across …

Noninvasive neuroimaging has revolutionized the study of the organization of the human
brain and how its structure and function are altered in psychiatric disorders. A critical …

Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and
affects individuals of all ages. It causes significant psychosocial impairments and is a major …

Genetic discoveries about human brain development and neuropsychiatric syndromes have
changed the landscape of psychiatric research. The genotyping of hundreds of thousands of …

Schizophrenia presents clinical and biological differences between males and females. This
study investigated transcriptional profiles in the dorsolateral prefrontal cortex (DLPFC) using …

Early onset schizophrenia (EOS, defined as first onset of schizophrenia before age 18) is a
rare form of schizophrenia (SCZ). Though genome-wide association studies (GWASs) have …

Genome-wide association studies (GWAS) for late stage age-related macular degeneration
(AMD) have identified 52 independent genetic variants with genome-wide significance at 34 …

Schizophrenia is a highly heritable, polygenic disorder. A growing list of common genetic
variants have been associated with schizophrenia; there is a clear need to understand the …

Background Seed oil content is an important agronomic trait of Brassica napus (B. napus),
and metabolites are considered as the bridge between genotype and phenotype for physical …