Introduction: Glucocorticoids represent the standard therapy for reducing inflammation and
immune activation in various diseases. However, as with any potent medication, they are not …

Glucocorticoid drugs interact with bone metabolism at many levels, but their principal action
is to reduce osteoblast number and bone matrix synthesis. Virtually all patients receiving …

Using prospective data from the Canadian Multicentre Osteoporosis Study (CaMos), we
compared health utilities index (HUI) scores after 5 years of follow-up among participants …

Bone is a complex biological material that consists of both an inorganic and organic phase,
which undergoes continuous dynamic biological processes within the body. This complex …

Backgroud: Elevated prolactin (hyperprolactinemia) has been commonly reported during
treatment with some an-tipsychotic drugs. A decrease in bone mineral density (BMD) may be …

Background Treatment with glucocorticoids is the leading cause of drug-induced
osteoporosis. Currently available guidelines indicate that patients receiving long-term …

Abstract Glucocorticoid (GC)-induced osteoporosis (GCOP) is the most common cause of
osteoporosis in adults aged 20–45 years as well as the most common cause of iatrogenic …

Osteoporosis is associated with low bone mass and microarchitectural deterioration of bone
tissue with clinical manifestation of low trauma fractures. Rheumatoid arthritis (RA) is a risk …

The development of secondary osteoporosis in rheumatoid arthritis (RA) has recently
become well recognized, characterized by demineralization at axial and in particular …

Corticosteroid (CS) therapy is widely used in the treatment of rheumatic diseases.
Osteoporosis remains one of its major complications. The risk of low bone mineral density …