Role of natural and synthetic compounds in modulating NRF2/KEAP1 signaling pathway in prostate cancer

G Tossetta, S Fantone, D Marzioni, R Mazzucchelli - Cancers, 2023 - mdpi.com
Simple Summary Several studies showed that oxidative stress is involved in cancer
occurrence, development, progression chemoresistance and radio resistance. The nuclear …

Natural flavonols: actions, mechanisms, and potential therapeutic utility for various diseases

AR Mahmud, TI Ema, MFR Siddiquee… - Beni-Suef University …, 2023 - Springer
Background Flavonols are phytoconstituents of biological and medicinal importance. In
addition to functioning as antioxidants, flavonols may play a role in antagonizing diabetes …

Preparation and characterization of lotus root starch based bioactive edible film containing quercetin-encapsulated nanoparticle and its effect on grape preservation

YF Zeng, YY Chen, YY Deng, C Zheng, CZ Hong… - Carbohydrate …, 2024 - Elsevier
The present work aimed to develop a novel bioactive edible film prepared by adding
quercetin-encapsulated carboxymethyl lotus root starch nanoparticles (QNPs), gellan gum …

[HTML][HTML] Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling …

L Li, W Jiang, B Yu, H Liang, S Mao, X Hu… - Biomedicine & …, 2023 - Elsevier
The modulation of microglial polarization from the pro-inflammatory M1 to the anti-
inflammatory M2 phenotype shows promise as a therapeutic strategy for ischemic stroke …

Pharmacological activity of flavonoid quercetin and its therapeutic potential in testicular injury

X Zhang, Y Tang, G Lu, J Gu - Nutrients, 2023 - mdpi.com
Quercetin is a natural flavonoid widely found in natural fruits and vegetables. Recent studies
have shown that quercetin mediates multiple beneficial effects in a variety of organ damage …

Advances in autophagy modulation of natural products in cervical cancer

T Tao, P Zhang, Z Zeng, M Wang - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Natural products play a critical role in drug development
and is emerging as a potential source of biologically active metabolites for therapeutic …

[HTML][HTML] A systematic review on immunity functionalities and nutritional food recommendations to develop immunity against viral infection

VK Pandey, A Tripathi, S Srivastava, S Pandey… - Applied Food …, 2023 - Elsevier
Immunity plays a fundamental role in the maintenance and protection of the human body
from infectious and pathogenic microorganisms. It requires regular intake of nutrients for …

Regulatory effects of quercetin on bone homeostasis: Research updates and future perspectives

Y Xi, J Shen, X Li, Y Bao, T Zhao, B Li… - The American Journal …, 2023 - World Scientific
The imbalance of bone homeostasis has become a major public medical problem amid the
background of an aging population, which is closely related to the occurrence of …

Fabrication and characterization of shellac nanofibers with colon-targeted delivery of quercetin and its anticancer activity

SF Li, TG Hu, YB Jin, H Wu - International Journal of Biological …, 2024 - Elsevier
In this study, the feasibility of shellac nanofibers as carrier system for colonic delivery of
quercetin was evaluated. Firstly, the nanofibers without and with different amounts (2.5 …

Antioxidant activity, anti-tyrosinase activity, molecular docking studies, and molecular dynamic simulation of active compounds found in nipa palm vinegar

M Chatatikun, A Tedasen, NC Pattaranggoon… - PeerJ, 2023 - peerj.com
Tyrosinase is a key enzyme in melanogenesis and its inhibitors have become increasingly
because of their potential activity as hypopigmenting agents which have less side effects …