Mechanisms and strategies to overcome PD-1/PD-L1 blockade resistance in triple-negative breast cancer

X Chen, L Feng, Y Huang, Y Wu, N Xie - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most prevalent malignancy in women. With the
improvement of medical treatment, breast cancer has become one of the solid tumors with …

Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression—3PM pathways

P Kubatka, A Mazurakova, M Samec, L Koklesova… - Epma Journal, 2021 - Springer
Inflammation is an essential pillar of the immune defense. On the other hand, chronic
inflammation is considered a hallmark of cancer initiation and progression. Chronic …

Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy

K Mortezaee, J Majidpoor - Cellular Oncology, 2022 - Springer
Macrophages are the most abundant and one of the most critical cells of tumor immunity.
They provide a bridge between innate and adaptive immunity through releasing cytokines …

Characterisation of the complete mitochondrial genome of Taraxacum mongolicum revealed five repeat-mediated recombinations

M Jiang, Y Ni, J Li, C Liu - Plant Cell Reports, 2023 - Springer
Key message We reported the mitochondrial genome of Taraxacum mongolicum for the first
time. Five pairs of repeats that can mediate recombination were validated, leading to …

Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies

J Liu, X Peng, S Yang, X Li, M Huang, S Wei… - Cell Communication and …, 2022 - Springer
Programmed cell death 1 ligand 1 (PD-L1) is the ligand for programmed death protein-1 (PD-
1), is associated with immunosuppression. Signaling via PD-1/PD-L1 will transmits negative …

Effect of tumor-associated macrophages on the pyroptosis of breast cancer tumor cells

XL Ji, X Huang, C Li, N Guan, T Pan, J Dong… - Cell Communication and …, 2023 - Springer
Macrophages are immune cells with high plasticity that are widely distributed in all tissues
and organs of the body. Under the influence of the immune microenvironment of breast …

Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling

P Zhu, Z Jin, G Kang, Y Jia, D Liu, Q Zhang… - Cell Communication and …, 2022 - Springer
Background Immunotherapy has proven to be an emerging treatment for non-small-cell lung
cancer in recent years. Notably, smokers show higher programmed cell death ligand-1 (PD …

Uncovering the mechanisms of dandelion against triple-negative breast cancer using a combined network pharmacology, molecular pharmacology and metabolomics …

J Qu, F Ke, Z Liu, X Yang, X Li, H Xu, Q Li, K Bi - Phytomedicine, 2022 - Elsevier
Background Taraxacum mongolicum, also called dandelion, has been used for thousands of
years as a remedy for mammary abscess, mammary gland hyperplasia, and various other …

Updates and advances on pharmacological properties of Taraxacum mongolicum Hand.-Mazz and its potential applications

Y Zhang, YF Hu, W Li, GY Xu, KR Wang, L Li, H Luo… - Food Chemistry, 2022 - Elsevier
As a well-recognized dietary and medicinal plant, Taraxacum mongolicum Hand.-Mazz
(TMHM) has been used for making wines, candies, energy drinks, and other functional …

The large molecular weight polysaccharide from wild cordyceps and its antitumor activity on H22 tumor-bearing mice

L Tan, S Liu, X Li, J He, L He, Y Li, C Yang, Y Li, Y Hua… - Molecules, 2023 - mdpi.com
Cordyceps has anti-cancer effects; however, the bioactive substance and its effect are still
unclear. Polysaccharides extracted from Cordyceps sinensis, the fugus of Cordyceps, have …