Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to genomic approaches

AT Marques, JMB Vítor, A Santos… - Microbial …, 2020 - microbiologyresearch.org
For a long time Helicobacter pylori infections have been treated using the macrolide
antibiotic, clarithromycin. Clarithromycin resistance is increasing worldwide and is the most …

Clinical Implication of Drug Resistance for H. pylori Management

EA Argueta, JJC Ho, Y Elfanagely, E D'Agata, SF Moss - Antibiotics, 2022 - mdpi.com
Rates of antimicrobial-resistance among H. pylori strains are increasing worldwide, resulting
in declining eradication rates with current therapies, especially those containing …

Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution

ES Cunha, X Chen, M Sanz-Gaitero, DJ Mills… - Nature …, 2021 - nature.com
Infection of the human stomach by Helicobacter pylori remains a worldwide problem and
greatly contributes to peptic ulcer disease and gastric cancer. Without active intervention …

Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA

A González, S Salillas, A Velázquez-Campoy… - Scientific reports, 2019 - nature.com
The increasing antibiotic resistance evolved by Helicobacter pylori has alarmingly reduced
the eradication rates of first-line therapies. To overcome the current circulating resistome, we …

In vitro antibacterial activity of nimbolide against Helicobacter pylori

MR Wylie, IH Windham, FC Blum, H Wu… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Nimbolide is one of hundreds of phytochemicals that have
been identified within the neem tree (Azadirachta indica A. Juss). As an evergreen tree …

Резистентность Helicobacter pylori в Российской Федерации: метаанализ исследований за последние 10 лет

ДН Андреев, ИВ Маев, ЮА Кучерявый - Терапевтический архив, 2020 - cyberleninka.ru
Цель. Систематизация данных о резистентности Helicobacter pylori к
антибактериальным препаратам в России за последние 10 лет. Методы. Поиск …

Antibiotic resistance of Helicobacter pylori isolated from patients in Nanjing, China: A cross-section study from 2018 to 2021

Z Jiang, X Qian, Z Wang, Y Dong, Y Pan… - Frontiers in cellular …, 2022 - frontiersin.org
The increasing antibiotic resistance of Helicobacter pylori infection is a globally urging
problem. To investigate the H. pylori resistance situation in Nanjing, China, we enrolled …

Молекулярно-генетические предикторы резистентности к антихеликобактерной терапии

ИВ Маев, ДН Андреев - Терапевтический архив, 2017 - cyberleninka.ru
В настоящее время в клинической практике отсутствует оптимальная эмпирическая
терапия инфекции Helicobacter pylori (H. pylori) и отмечается прогрессивное снижение …

Helicobacter pylori resistance in the Russian Federation: a meta-analysis of studies over the past 10 years

DN Andreev, IV Maev, YA Kucheryavyy - Terapevticheskii arkhiv, 2020 - ter-arkhiv.ru
Aim. Systematization of data on antibiotic resistance of Helicobacter pylori in Russia over the
past 10 years. Methods. A search for studies were carried out in electronic databases …

[HTML][HTML] Molecular genetic predictors of resistance to anti-Helicobacter pylori therapy

IV Maev, DN Andreev - Terapevticheskii arkhiv, 2017 - ter-arkhiv.ru
In current clinical practice, there is no optimal empirical therapy for Helicobacter pylori (H.
pylori) infection and there is a progressive decrease in the efficiency of classical eradication …