Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …

The Long COVID/Post Acute Sequelae of COVID-19 (PASC) group includes patients with
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …

Compelling experimental evidence links immunity and metabolism. In this perspective, we
propose forkhead-box-P3 (FoxP3)+ CD4+ CD25+ regulatory T (Treg) cells as key metabolic …

The main cause of death in patients with type 2 DM is cardiovascular complications resulting
from the progression of atherosclerosis. The pathophysiology of the association between …

The biguanide metformin has been used as first-line therapy in type 2 diabetes mellitus
(T2DM) treatment for several decades. In addition to its glucose-lowering properties and its …

Original research: Metformin increases natural killer cell functions in head and neck squamous
cell carcinoma through CXCL1 inhibition - PMC Back to Top Skip to main content NIH NLM …

An intricate interplay between genetic and environmental factors contributes to the
development of type 2 diabetes (T2D) and its complications. Therefore, it is not surprising …

The geroscience hypothesis posits that by targeting key hallmarks of aging we may
simultaneously prevent or delay several age-related diseases and thereby increase …

Metformin, a drug widely used in type 2 diabetes (T2D), has been shown to protect human β-
cells exposed to gluco-and/or lipotoxic conditions and those in islets from T2D donors. We …

Nutrition affects all physiological processes occurring in our body, including those related to
the function of the immune system; indeed, metabolism has been closely associated with the …