The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

J Nikolich-Zugich, KS Knox, CT Rios, B Natt… - Geroscience, 2020 - Springer
Abstract SARS-CoV-2 virus, the causative agent of the coronavirus infectious disease-19
(COVID-19), is taking the globe by storm, approaching 500,000 confirmed cases and over …

Myocardial injury and COVID-19: possible mechanisms

S Babapoor-Farrokhran, D Gill, J Walker, RT Rasekhi… - Life sciences, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) has quickly progressed to a global health
emergency. Respiratory illness is the major cause of morbidity and mortality in these …

COVID-19: specific and non-specific clinical manifestations and symptoms: the current state of knowledge

J Baj, H Karakuła-Juchnowicz, G Teresiński… - Journal of clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19), due to the severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), has become an epidemiological threat and a worldwide …

Lessons for COVID-19 immunity from other coronavirus infections

A Sariol, S Perlman - Immunity, 2020 - cell.com
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …

[HTML][HTML] Molecular immune pathogenesis and diagnosis of COVID-19

X Li, M Geng, Y Peng, L Meng, S Lu - Journal of pharmaceutical analysis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The emergence of …

Lymphopenia in COVID‐19: Therapeutic opportunities

N Fathi, N Rezaei - Cell biology international, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is uncontrollably spread
all over the world. The host immune responses strongly try to confront it with all the potential …

Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China

R Chen, L Sang, M Jiang, Z Yang, N Jia, W Fu… - Journal of Allergy and …, 2020 - Elsevier
Background Crucial roles of hematologic and immunologic responses in progression of
coronavirus disease 2019 (COVID-19) remain largely unclear. Objective We sought to …

Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

JF Bermejo-Martin, M González-Rivera, R Almansa… - Critical Care, 2020 - Springer
Background COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-
2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID …

Virology, pathogenesis, diagnosis and in-line treatment of COVID-19

PK Samudrala, P Kumar, K Choudhary… - European journal of …, 2020 - Elsevier
Abstract SARS-CoV-2, a newly emerged pathogen in December 2019, marked as one of the
highly pathogenic Coronavirus, and altogether this is the third coronavirus attack that …