The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …

Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …

The role of conventional serum tumor marker carbohydrate antigen 72-4 (CA72-4) in
assisting diagnosis, monitoring dynamic progression, and evaluating the prognosis of …

Gastrointestinal cancer (GIC) is a common malignant tumour of the digestive system that
seriously threatens human health. Due to the unique organ structure of the gastrointestinal …

Colon cancer etiology involves a wide spectrum of genetic and epigenetic alterations,
finding it challenging to find effective therapeutic strategies. Quercetin exhibits potent anti …

Background Tumor-infiltrating lymphocytes (TILs), especially CD8+ TILs, can be used for
predicting immunotherapy responsiveness and survival outcome. However, the evaluation …

As the most aggressive tumor, the outcome of pancreatic cancer (PACA) has not improved
observably over the last decade. Anatomy-based TNM staging does not exactly identify …

Hepatocellular carcinoma (HCC) is one of the most lethal neoplasms and has a 5-year
survival rate of only 18% in patients with metastatic diseases. Epigenetic modifiers and …

In recent years, the tumour microenvironment (TME) of solid tumours has attracted more and
more attention from researchers, especially those non-tumour components such as immune …

Gastric cancer is a gastrointestinal tumor with high morbidity and mortality rates. Several
factors influence its progression, cell death being an important element. In this review, we …