[HTML][HTML] MicroRNAs in the development of potential therapeutic targets against COVID-19: A narrative review

JQ Ahmed, SQ Maulud, M Dhawan… - Journal of Infection and …, 2022 - Elsevier
Background As the therapeutic regimens against the COVID-19 remain scarce, the
microRNAs (miRNAs) can be exploited to generate efficient therapeutic targets. The miRNAs …

[HTML][HTML] Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections

AH de Nooijer, P Pickkers, MG Netea, M Kox - Journal of Critical Care, 2023 - Elsevier
Mortality in acute infections is mostly associated with sepsis, defined as 'life-threatening
organ dysfunction caused by a dysregulated host response to infection'. It remains …

Counter-regulatory renin-angiotensin system in hypertension: Review and update in the era of COVID-19 pandemic

H Chen, J Peng, T Wang, J Wen, S Chen… - Biochemical …, 2023 - Elsevier
Cardiovascular disease is the major cause of mortality and disability, with hypertension
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …

miRNAs as a potential biomarker in the COVID-19 infection and complications course, severity, and outcome

M Jankovic, D Nikolic, I Novakovic, B Petrovic… - Diagnostics, 2023 - mdpi.com
During the last three years, since the emergence of the COVID-19 pandemic, a significant
number of scientific publications have focused on resolving susceptibility to the infection, as …

Emerging role of microRNAs and long non-coding RNAs in COVID-19 with implications to therapeutics

K Arman, Z Dalloul, E Bozgeyik - Gene, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection which is
commonly known as COVID-19 (COronaVIrus Disease 2019) has creeped into the human …

Dysregulated miRNAs network in the critical COVID-19: An important clue for uncontrolled immunothrombosis/thromboinflammation

SS Mortazavi-Jahromi, M Aslani - International Immunopharmacology, 2022 - Elsevier
Known as a pivotal immunohemostatic response, immunothrombosis is activated to restrict
the diffusion of pathogens. This beneficial intravascular defensive mechanism represents …

MicroRNAs and proteolytic cleavage of receptors in cancers: A comprehensive review of regulatory interactions and therapeutic implications

F Hosseinpour-Soleimani, Z Salmasi, Y Ghasemi… - Heliyon, 2024 - cell.com
Cancer remains a challenging disease worldwide, necessitating innovative approaches to
better comprehend its underlying molecular mechanisms and devise effective therapeutic …

Evaluation of angiotensin converting enzyme 2 (ACE2), angiotensin II (Ang II), miR-141-3p, and miR-421 levels in SARS-CoV-2 patients: a case-control study

E Kakavandi, K Sadeghi, M Shayestehpour… - BMC Infectious …, 2024 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
contagious virus that uses angiotensin converting enzyme 2 (ACE2), a pivotal member of the …

Computational Prediction of RNA–RNA Interactions between Small RNA Tracks from Betacoronavirus Nonstructural Protein 3 and Neurotrophin Genes during …

AF Rojas-Cruz, CI Bermúdez-Santana - Viruses, 2023 - mdpi.com
Whether RNA–RNA interactions of cytoplasmic RNA viruses, such as Betacoronavirus,
might end in the biogenesis of putative virus-derived small RNAs as miRNA-like molecules …

Increased serum mir-150-3p expression is associated with radiological lung injury improvement in patients with covid-19

LCM Bueno, LR Paim, EOZ Minin, LM da Silva… - Viruses, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by the SARS-CoV-2 virus, responsible for
an atypical pneumonia that can progress to acute lung injury. MicroRNAs are small non …