Chitosan nanoparticles (NPs) are promising polymeric and bio-based NPs, which have
received a lot of attention in the last decades. They have great potential as nanocarriers that …

Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Polymers are used in drug delivery devices for drug encapsulation and release. Natural
polymers often have advantages such as biocompatibility, biodegradability and biologically …

Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …

Spray-drying is a rapid, continuous, cost-effective, reproducible and scalable process for the
production of dry powders from a fluid material by atomization through an atomizer into a hot …

Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

Local ocular delivery of cyclosporine A (CsA) is the preferred method for CsA delivery as a
treatment for ocular inflammatory diseases such as uveitis, corneal healing, vernal …

Chitin-based nanoparticles are polysaccharide materials that can be produced from a waste
stream of the seafood industry: crustacean shells. These nanoparticles have received …

The main inconvenience of conventional eye drops is the rapid washout of the drugs due to
nasolacrimal drainage or ophthalmic barriers. The ocular drug bioavailability can be …

Cyclosporine is an immunosuppressant agent approved for the treatment of dry eye disease
and used off-label for other ocular pathologies. Its formulation and ocular bioavailability …