Heterozygous NRXN1 deletions constitute the most prevalent currently known single-gene
mutation associated with schizophrenia, and additionally predispose to multiple other …

Despite considerable progress in schizophrenia genetics, most findings have been for large
rare structural variants and common variants in well-imputed regions with few genes …

Probiotics are currently the subject of intensive research pursuits and also represent a multi-
billion-dollar global industry given their vast potential to improve human health. In addition …

Depression is a leading cause of worldwide disability but there remains considerable
uncertainty regarding its neural and behavioural associations. Here, using non-overlapping …

The field of probiotic has been exponentially expanding over the recent decades with a
more therapeutic-centered research. Probiotics mediated microbiota modulation within the …

We conducted a two-sample Mendelian randomization study to determine the association of
smoking initiation with seven psychiatric disorders. We used 353 independent single …

To provide insights into the biology of opioid dependence (OD) and opioid use (ie,
exposure, OE), we completed a genome-wide analysis comparing 4503 OD cases, 4173 …

Psychiatric disorders are highly genetically correlated, but little research has been
conducted on the genetic differences between disorders. We developed a new method …

Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

Background Recent genome-wide association studies (GWASs) have revealed the
polygenic nature of psychiatric disorders and discovered a few of single-nucleotide …