Messenger RNA (mRNA) has received great attention in the prevention and treatment of
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …

Many pharmaceutically active molecules are highly lipophilic, which renders their
administration and adsorption in patients extremely challenging. Among the countless …

We report on a novel strategy for treating liver fibrosis through reprogramming activated
Hepatic Stellate Cells (aHSCs) into quiescent Hepatic Stellate Cells (qHSCs) using siRNA …

Lung cancer is one of the most aggressive and deadliest health threats. There has been an
increasing interest in non-coding RNA (ncRNA) recently, especially in the areas of …

Objective and significance Silver nanoparticles (AgNPs) have become an interesting
therapeutic modality and drug delivery platform. Herein, we aimed to investigate the impact …

Breast cancer is a wide-spread threat to the women's health. The drawbacks of conventional
treatments necessitate the development of alternative strategies, where gene therapy has …

Despite recent advancements in cancer treatment, this disease still poses a serious threat to
public health. Vaccines play an important role in preventing illness by preparing the body's …

Background Therapeutic resistance fails cancer treatment. Drug-nanoparticle combinations
overcome resistance. Sanguinarine-conjugated nanoparticles may boost sanguinarine's …

With the increment of the aging population in recent years, neurodegenerative diseases
exert a major global disease burden, essentially as a result of the lack of treatments that stop …

Cholesterol (CHOL) is essential for developing lipid nanoparticles (LNPs) for gene delivery
because it enhances membrane fusion and improves the delivery efficiency of gene cargos …