[HTML][HTML] Pharmacologically inducing anoikis offers novel therapeutic opportunities in hepatocellular carcinoma

Y Wang, JS Fleishman, J Wang, J Chen, L Zhao… - Biomedicine & …, 2024 - Elsevier
Tumor metastasis occurs in hepatocellular carcinoma (HCC), leading to tumor progression
and therapeutic failure. Anoikis is a matrix detachment-induced apoptosis, also known as …

Chitosan-and hyaluronic acid-based nanoarchitectures in phototherapy: Combination cancer chemotherapy, immunotherapy and gene therapy

Z Wang, S Pang, X Liu, Z Dong, Y Tian… - International Journal of …, 2024 - Elsevier
Cancer phototherapy has introduced a new potential modality for tumor suppression.
However, the efficacy of phototherapy has been limited due to a lack of targeted delivery of …

Size and Surface Properties of Functionalized Organosilica Particles Impact Cell–Particle Interactions Including Mitochondrial Activity

J Nakamura, Y Shiohama, D Röth… - … Applied Materials & …, 2024 - ACS Publications
Understanding of the interactions between macrophages and multifunctional nanoparticles
is important for development of novel macrophage-based immunotherapies. Here, we …

[HTML][HTML] Revolutionizing Glioblastoma Treatment: A Comprehensive Overview of Modern Therapeutic Approaches

K Sadowski, A Jażdżewska, J Kozłowski… - International Journal of …, 2024 - mdpi.com
Simple Summary Glioblastoma is one of the most dangerous tumors of the central nervous
system, and still cannot be fully overcome. We still mainly rely on standard treatments …

Role of microRNAs in tumor progression by regulation of kinesin motor proteins

AN Shad, A Fanoodi, A Maharati, I Akhlaghipour… - International Journal of …, 2024 - Elsevier
Aberrant cell proliferation is one of the main characteristics of tumor cells that can be
affected by many cellular processes and signaling pathways. Kinesin superfamily proteins …

The Multifaceted Role of SOX2 in Breast and Lung Cancer Dynamics

K Hushmandi, SH Saadat, S Mirilavasani… - … -Research and Practice, 2024 - Elsevier
Breast and lung cancers are leading causes of death among patients, with their global
mortality and morbidity rates increasing. Conventional treatments often prove inadequate …

The Science of Exosomes: Understanding Their Formation, Capture, and Role in Cellular Communication

K Hushmandi, SH Saadat, M Raei, AR Aref… - … -Research and Practice, 2024 - Elsevier
Extracellular vesicles (EVs) serve as a crucial method for transferring information among
cells, which is vital in multicellular organisms. Among these vesicles, exosomes are notable …

Implications of c-Myc in the Pathogenesis and Treatment Efficacy of Urological Cancers

K Hushmandi, SH Saadat, M Raei, S Daneshi… - … -Research and Practice, 2024 - Elsevier
Urological cancers, including prostate, bladder, and renal cancers, are significant causes of
death and negatively impact the quality of life for patients. The development and progression …

[HTML][HTML] Overexpression of SYNGAP1 suppresses the proliferation of rectal adenocarcinoma via Wnt/β-Catenin signaling pathway

Y Xiao, Y Zhu, J Chen, M Wu, L Wang, L Su, F Feng… - Discover Oncology, 2024 - Springer
Rectal adenocarcinoma (READ) is a common malignant tumor of the digestive tract.
Growing studies have confirmed Ras GTPase-activating proteins are involved in the …

Immunotherapy of breast cancer with folate targeted PLGA nanoparticles photothermal therapy combined with checkpoint CTLA4 blocking

C HU, Q Ke, Y Jiang, Z Wu, Y Chen, Z Wu, Q Zhang… - 2024 - researchsquare.com
Background Breast cancer is one of the most serious diseases facing human health.
Nanomedicine has conducted extensive research in the diagnosis and treatment of tumors …