Common dysfunction of large-scale neurocognitive networks across psychiatric disorders
Background Cognitive dysfunction is one of the most prominent characteristics of psychiatric
disorders. Currently, the neural correlates of cognitive dysfunction across psychiatric …
disorders. Currently, the neural correlates of cognitive dysfunction across psychiatric …
[HTML][HTML] Gamma oscillations as a biomarker for major depression: an emerging topic
PJ Fitzgerald, BO Watson - Translational psychiatry, 2018 - nature.com
Identifying biomarkers for major depression is of high importance for improving diagnosis
and treatment of this common and debilitating neuropsychiatric disorder, as the field seeks …
and treatment of this common and debilitating neuropsychiatric disorder, as the field seeks …
Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study
Objective To examine associations between early developmental exposure to ambient
pesticides and autism spectrum disorder. Design Population based case-control study …
pesticides and autism spectrum disorder. Design Population based case-control study …
Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes
Most studies of gene expression in the brains of individuals with schizophrenia have
focused on cortical regions, but subcortical nuclei such as the striatum are prominently …
focused on cortical regions, but subcortical nuclei such as the striatum are prominently …
[HTML][HTML] Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis
Epilepsy is one of the most common neurological disorders, yet its pathophysiology is poorly
understood due to the high complexity of affected neuronal circuits. To identify dysfunctional …
understood due to the high complexity of affected neuronal circuits. To identify dysfunctional …
Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes
Schizophrenia has been conceived as a disorder of brain connectivity, but it is unclear how
this network phenotype is related to the underlying genetics. We used morphometric …
this network phenotype is related to the underlying genetics. We used morphometric …
Long-term risk of neuropsychiatric disease after exposure to infection in utero
BJS Al-Haddad, B Jacobsson, S Chabra… - JAMA …, 2019 - jamanetwork.com
Importance The developmental origins of mental illness are incompletely understood.
Although the development of autism and schizophrenia are linked to infections during fetal …
Although the development of autism and schizophrenia are linked to infections during fetal …
[HTML][HTML] Getting to the cores of autism
The genetic architecture of autism spectrum disorder (ASD) is itself a diverse allelic
spectrum that consists of rare de novo or inherited variants in hundreds of genes and …
spectrum that consists of rare de novo or inherited variants in hundreds of genes and …
Genetics of substance use disorders in the era of big data
J Gelernter, R Polimanti - Nature Reviews Genetics, 2021 - nature.com
Substance use disorders (SUDs) are conditions in which the use of legal or illegal
substances, such as nicotine, alcohol or opioids, results in clinical and functional …
substances, such as nicotine, alcohol or opioids, results in clinical and functional …
[HTML][HTML] Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD
Neuropsychiatric disorders classically lack defining brain pathologies, but recent work has
demonstrated dysregulation at the molecular level, characterized by transcriptomic and …
demonstrated dysregulation at the molecular level, characterized by transcriptomic and …