Third‐generation sequencing of epigenetic DNA

B Searle, M Müller, T Carell, A Kellett - Angewandte Chemie, 2023 - Wiley Online Library
The discovery of epigenetic bases has revolutionised the understanding of disease and
development. Among the most studied epigenetic marks are cytosines covalently modified at …

Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19

A Valenzuela-Fernández… - … in Bioengineering and …, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the
associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory …

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

AP Ugalde, G Bretones, D Rodríguez… - The EMBO …, 2022 - embopress.org
Better understanding on interactions between SARS‐CoV‐2 and host cells should help to
identify host factors that may be targetable to combat infection and COVID‐19 pathology. To …

Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping

K Rubben, L Tilleman, K Deserranno, O Tytgat… - PLoS …, 2022 - journals.plos.org
CYP2D6 is a very important pharmacogene as it is responsible for the metabolization or
bioactivation of 20 to 30% of the clinically used drugs. However, despite its relatively small …

Nanopore sequencing of SARS-CoV-2: Comparison of short and long PCR-tiling amplicon protocols

B Brejová, K Boršová, V Hodorová, V Čabanová… - PLoS …, 2021 - journals.plos.org
Surveillance of the SARS-CoV-2 variants including the quickly spreading mutants by rapid
and near real-time sequencing of the viral genome provides an important tool for effective …

Diagnosis of pathogens causing bacterial meningitis using Nanopore sequencing in a resource-limited setting

SR Pallerla, D Van Dong, LTK Linh, T Van Son… - Annals of Clinical …, 2022 - Springer
Aim The aim of the present study is to compare the performance of 16S rRNA Nanopore
sequencing and conventional culture in detecting infectious pathogens in patients with …

Receptor-binding-motif-targeted sanger sequencing: a quick and cost-effective strategy for molecular surveillance of SARS-coV-2 variants

SP Chaki, MM Kahl-McDonagh, BW Neuman… - Microbiology …, 2022 - Am Soc Microbiol
Whole-genome sequencing (WGS) is the gold standard for characterizing the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and identification of new …

Needs, challenges and countermeasures of SARS-CoV-2 surveillance in cold-chain foods and packaging to prevent possible COVID-19 resurgence: a perspective …

Y Li, J Qiao, X Han, Z Zhao, J Kou, W Zhang, S Man… - Viruses, 2022 - mdpi.com
The pandemic caused by SARS-CoV-2 has a huge impact on the global economy. SARS-
CoV-2 could possibly and potentially be transmitted to humans through cold-chain foods …

CalmBelt: rapid SARS-CoV-2 genome characterization for outbreak tracking

H Yingtaweesittikul, K Ko, N Abdul Rahman… - Frontiers in …, 2021 - frontiersin.org
Background: The ongoing COVID-19 pandemic is a global health crisis caused by the
spread of SARS-CoV-2. Establishing links between known cases is crucial for the …

A high scale SARS-CoV-2 profiling by its whole-genome sequencing using Oxford Nanopore Technology in Kazakhstan

U Kairov, A Amanzhanova, D Karabayev… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome (SARS-CoV-2) is responsible for the worldwide
pandemic, COVID-19. The original viral whole-genome was sequenced by a high …