[HTML][HTML] Targeting IL-6 trans-signalling: past, present and future prospects
S Rose-John, BJ Jenkins, C Garbers, JM Moll… - Nature Reviews …, 2023 - nature.com
Abstract Interleukin-6 (IL-6) is a key immunomodulatory cytokine that affects the
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …
[HTML][HTML] Biomarkers in COVID-19: an up-to-date review
M Samprathi, M Jayashree - Frontiers in pediatrics, 2021 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19) poses several challenges
to clinicians. Timely diagnosis and hospitalization, risk stratification, effective utilization of …
to clinicians. Timely diagnosis and hospitalization, risk stratification, effective utilization of …
Emerging telemedicine tools for remote COVID-19 diagnosis, monitoring, and management
The management of the COVID-19 pandemic has relied on cautious contact tracing,
quarantine, and sterilization protocols while we await a vaccine to be made widely available …
quarantine, and sterilization protocols while we await a vaccine to be made widely available …
Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
Y Zhang, V Bharathi, T Dokoshi… - Proceedings of the …, 2024 - National Acad Sciences
It is unclear how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
leads to the strong but ineffective inflammatory response that characterizes severe …
leads to the strong but ineffective inflammatory response that characterizes severe …
[HTML][HTML] SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells
Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2
infection, although the mechanism for initiation of a hyper-inflammatory response, and multi …
infection, although the mechanism for initiation of a hyper-inflammatory response, and multi …
[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
Soft wearable healthcare materials and devices
In spite of advances in electronics and internet technologies, current healthcare remains
hospital‐centred. Disruptive technologies are required to translate state‐of‐art wearable …
hospital‐centred. Disruptive technologies are required to translate state‐of‐art wearable …
[HTML][HTML] Longitudinal cytokine profile in patients with mild to critical COVID-19
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …
[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications
C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …
[HTML][HTML] Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain
SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …