Immunoglobulin M (IgM) is the first type of antibody produced during acute infections and
thus provides an early line of specific defense against pathogens. Being produced in …

A large number of neutrophils infiltrate the lymph node (LN) within 4 h after Staphylococcus
aureus skin infection (4 h postinfection [hpi]) and prevent systemic S. aureus dissemination …

The human lymphatic system (HLS) is a complex network of lymphatic organs linked through
the lymphatic vessels. We present a graph theory-based approach to model and analyze the …

Chronic imaging windows in mice have been developed to allow intravital microscopy of
many different organs and have proven to be of paramount importance in advancing our …

The motion of the lymph has a very important role in the immune system, and it is influenced
by the porosity of the lymph nodes: more than 90% takes the peripheral path without …

This review will highlight our current understanding of the formation, circulation, and
immunological role of lymphatic fluid. The formation of the extracellular fluid depends on the …

The role of microenvironment-mediated biophysical forces in human lymphomas remains
elusive. Diffuse large B cell lymphomas (DLBCLs) are heterogeneous tumors, which …

Despite the growing popularity of subcutaneous (SC) administration for monoclonal
antibodies (mAbs), there remains a limited understanding of the significance of mAb …

The lymphatic system is a complex organ system that is essential in regulating the
development of host immune responses. Because of the complexity of the lymphatic system …

This paper presents current knowledge about the structure and function of the lymphatic
system. Mathematical models of lymph flow in the single lymphangion, the series of …