Integrative computational modeling of the lymph node stromal cell landscape

M Novkovic, L Onder, HW Cheng, G Bocharov… - Frontiers in …, 2018 - frontiersin.org
Adaptive immune responses develop in secondary lymphoid organs such as lymph nodes
(LNs) in a well-coordinated series of interactions between migrating immune cells and …

Lymphatic cannulation for lymph sampling and molecular delivery

DC Zawieja, S Thangaswamy, W Wang… - The Journal of …, 2019 - journals.aai.org
Unlike the blood, the interstitial fluid and the deriving lymph are directly bathing the cellular
layer of each organ. As such, composition analysis of the lymphatic fluid can provide more …

[HTML][HTML] A novel computational model predicts key regulators of chemokine gradient formation in lymph nodes and site-specific roles for CCL19 and ACKR4

M Jafarnejad, DC Zawieja, BS Brook… - The Journal of …, 2017 - journals.aai.org
The chemokine receptor CCR7 drives leukocyte migration into and within lymph nodes
(LNs). It is activated by chemokines CCL19 and CCL21, which are scavenged by the …

Three-dimensional analyses of vascular network morphology in a murine lymph node by X-ray phase-contrast tomography with a 2D Talbot array

FL Schwarzenberg, P Schütz, JU Hammel… - Frontiers in …, 2022 - frontiersin.org
With growing molecular evidence for correlations between spatial arrangement of blood
vasculature and fundamental immunological functions, carried out in distinct compartments …

In vitro, in vivo, and in silico models of lymphangiogenesis in solid malignancies

S Bekisz, L Baudin, F Buntinx, A Noël, L Geris - Cancers, 2022 - mdpi.com
Simple Summary Lymphangiogenesis is the formation of new lymphatic vessels in
physiological conditions but has also been found to be associated with pathologies. For …

Mathematical modeling of lymph node drainage function by neural network

R Tretiakova, A Setukha, R Savinkov, D Grebennikov… - Mathematics, 2021 - mdpi.com
The lymph node (LN) represents a key structural component of the lymphatic system network
responsible for the fluid balance in tissues and the immune system functioning. Playing an …

The T cell journey: a tour de force

A Alatoom, M ElGindi, J Sapudom… - Advanced Biology, 2023 - Wiley Online Library
T cells act as the puppeteers in the adaptive immune response, and their dysfunction leads
to the initiation and progression of pathological conditions. During their lifetime, T cells …

Quantification of the whole lymph node vasculature based on tomography of the vessel corrosion casts

M Jafarnejad, AZ Ismail, D Duarte, C Vyas… - Scientific Reports, 2019 - nature.com
Lymph nodes (LN) are crucial for immune function, and comprise an important interface
between the blood and lymphatic systems. Blood vessels (BV) in LN are highly specialized …

Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria

MJ Haley, R Barroso, DA Jasim, M Haigh, J Green… - Cell Reports, 2024 - cell.com
While brain swelling, associated with fluid accumulation, is a known feature of pediatric
cerebral malaria (CM), how fluid and macromolecules are drained from the brain during …

The compartments of the parenchyma of the lymph nodes in the newborn bull calves of domestic cattle (Bos taurus).

PN Gavrilin, OG Gavrilina, MV Kravtsova - 2017 - cabidigitallibrary.org
The article analyzes the features of the structure of the lymphoid lobules of the parenchyma
of the superficial somatic (Limphonodi subiliaci, L. cervicales superficiales), profund somatic …