Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS)
are life-threatening hyperferritinemic systemic inflammatory disorders. Although profound …

The article focuses on cytokine storm syndrome which is a diverse set of conditions unified
by a clinical phenotype of systemic inflammation, multi-organ failure and hyperferritinemia …

Macrophage activation syndrome (MAS) refers to acute overwhelming inflammation caused
by a'cytokine storm'. Although increasingly recognized as a life-threatening complication of …

A hyperinflammatory 'cytokine storm'state termed macrophage activation syndrome (MAS),
culminating from a complex interplay of genetics, immunodeficiency, infectious triggers and …

Macrophage activation syndrome (MAS) is an acute episode of overwhelming inflammation
characterized by activation and expansion of T lymphocytes and hemophagocytic …

Objective Systemic juvenile idiopathic arthritis (JIA) is associated with high levels of
interleukin‐6 (IL‐6) in the serum and synovial fluid, and impairment of natural killer (NK) cell …

Objectives Interferon-γ (IFNγ) is the pivotal mediator in murine models of primary
haemophagocytic lymphohistiocytosis (pHLH). Given the similarities between primary and …

An analysis of published data appertaining to the cytokine storms of COVID-19, H1N1
influenza, cytokine release syndrome (CRS), and macrophage activation syndrome (MAS) …

Macrophage activation syndrome (MAS), a form of secondary hemophagocytic
lymphohistiocytosis, is a frequently fatal complication of a variety of pediatric inflammatory …

Several new discoveries have revived interest in the pathogenic potential and possible
clinical roles of IL-18. IL-18 is an IL-1 family cytokine with potent ability to induce IFNγ …