The adequate availability and metabolism of three essential trace elements, iodine,
selenium and iron, provide the basic requirements for the function and action of the thyroid …

Thyroid function affects multiple sites of the female hypothalamic-pituitary gonadal (HPG)
axis. Disruption of thyroid function has been linked to reproductive dysfunction in women …

Abstract Chronic Fatigue Syndrome (CFS) presents with symptoms of hypothyroidism,
including mental and physical fatigue, poor sleep, depression, and anxiety. However, thyroid …

Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

Thyroid hormones (TH) play critical roles during nervous system development and patients
carrying coding variants of MCT8 (monocarboxylate transporter 8) or THRA (thyroid …

The energy homeostasis of the organism is orchestrated by a complex interplay of energy
substrate shuttling, breakdown, storage, and distribution. Many of these processes are …

Thyroid hormones play an essential role in regulating whole-body homeostasis.
Deiodinases are known to convert thyroid hormone from the prohormone thyroxine (T4) to …

G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors, and
Takeda G protein-coupled receptor 5 (TGR5) is a member of this family. As a membrane …

Background Genome-wide association studies (GWAS) have identified genetic variants
linked to fat metabolism and related traits, but rarely pinpoint causative variants. This …

We review the evidence regarding the nongenomic (or non-canonical) actions of thyroid
hormones (thyronines) and their derivatives (including thyronamines and thyroacetic acids) …