Background Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of
treatment to prevent thrombotic complications of acute coronary syndromes and …

Acute myocardial infarction has traditionally been divided into ST elevation or non-ST
elevation myocardial infarction; however, therapies are similar between the two, and the …

For more than 10 years, dual antiplatelet therapy with aspirin and clopidogrel has remained
the cornerstone of treatment for patients with acute coronary syndrome (ACS). The novel …

In patients with manifestations of cardiovascular disease, acetylsalicylic acid (popularly
known as aspirin) has been the mainstay of treatment for decades owing to its capacity to …

Document Reviewers: Sigmund Silber (CPG Review Coordinator)(Germany), Frank V.
Aguirre (USA), Nawwar Al-Attar (France), Eduardo Alegria (Spain), Felicita Andreotti (Italy) …

The term acute coronary syndrome (ACS) refers to any group of clinical symptoms
compatible with acute myocardial ischemia and includes unstable angina (UA), non—ST …

This review of the role of platelets in atherothrombosis illuminates the surprisingly numerous
activities of these tiny, anucleate cells and stresses their participation in the inflammatory …

Background Pharmacogenetic determinants of the response of patients to clopidogrel
contribute to variability in the biologic antiplatelet activity of the drug. The effect of these …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through November 2010, as well as selected …

Background Dual antiplatelet therapy with clopidogrel plus low-dose aspirin has not been
studied in a broad population of patients at high risk for atherothrombotic events. Methods …