Unpublished and misreported studies make it difficult to determine the true value of a
treatment. Peter Doshi and colleagues call for sponsors and investigators of abandoned …

АСБ—атеросклеротическая бляшка АВ—атриовентрикулярный АВС—активированное
время свертывания крови AГ—артериальная гипертензия АД—артериальное давление …

Abstract P2Y12, the Gi-coupled platelet receptor for adenosine diphosphate (ADP), plays a
central role in platelet function. Patients with congenital P2Y12 defects display a mild to …

Steven M. Ettinger, MD, FACC, Robert A. Guyton, MD, FACC, Jonathan L. Halperin, MD,
FACC, FAHA, Judith S. Hochman, MD, FACC, FAHA, Frederick G. Kushner, MD, FACC …

The past 2 decades have witnessed the introduction and demise of several different
antithrombotic medications for acute coronary syndromes. Part of the assessment of these …

The following chapter devoted to antithrombotic therapy for chronic coronary artery disease
(CAD) is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest …

Background—The glycoprotein IIb/IIIa receptor inhibitor abciximab has improved the efficacy
of primary percutaneous coronary interventions in patients with acute myocardial infarction …

Background Ticagrelor is an oral P2Y12 inhibitor that is used with aspirin to reduce the risk
of ischemic events among patients with acute coronary syndromes or previous myocardial …

In the PLATelet inhibition and patient Outcomes (PLATO) study of patients with acute
coronary syndromes, ticagrelor reduced mortality compared to clopidogrel but the …

Background and Purpose—We sought to determine the incidence and severity of bleeding
events in patients with stroke and cardiovascular diseases who were taking oral …