Atherosclerosis: current pathogenesis and therapeutic options

C Weber, H Noels - Nature medicine, 2011 - nature.com
Coronary artery disease (CAD) arising from atherosclerosis is a leading cause of death and
morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism …

LOX‐1, OxLDL, and atherosclerosis

A Pirillo, GD Norata, AL Catapano - Mediators of inflammation, 2013 - Wiley Online Library
Oxidized low‐density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation
and progression by several mechanisms, including the induction of endothelial cell …

Platelets mediate inflammatory monocyte activation by SARS-CoV-2 spike protein

T Li, Y Yang, Y Li, Z Wang, F Ma, R Luo… - The Journal of …, 2022 - Am Soc Clin Investig
Infection with SARS-CoV-2, the causative agent of COVID-19, causes mild to moderate
disease in most patients but carries a risk of morbidity and mortality. Seriously affected …

Extra virgin olive oil: More than a healthy fat

EM Yubero-Serrano, J Lopez-Moreno… - European journal of …, 2019 - nature.com
The beneficial effects of a Mediterranean diet on human health and, in particular, on
lowering risk of cardiovascular disease, has been mainly attributed to its high content to …

The hemostatic system as a modulator of atherosclerosis

JI Borissoff, HMH Spronk… - New England Journal of …, 2011 - Mass Medical Soc
The Hemostatic System as a Modulator of Atherosclerosis | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

[HTML][HTML] Platelet-leukocyte interplay during vascular disease

WC Schrottmaier, M Mussbacher, M Salzmann… - Atherosclerosis, 2020 - Elsevier
Vascular disease is a progressive inflammatory condition fuelled by an unhealthy lifestyle of
physical inactivity, cholesterol-rich diet, and smoking. Together with endogenous factors …

Immune Checkpoint Therapies and Atherosclerosis: Mechanisms and Clinical Implications: JACC State-of-the-Art Review

JT Vuong, AF Stein-Merlob, A Nayeri, T Sallam… - Journal of the American …, 2022 - jacc.org
Immune checkpoint inhibitor therapy has revolutionized the treatment of advanced
malignancies in recent years. Numerous reports have detailed the myriad of possible …

The influence of innate and adaptive immune responses on atherosclerosis

JL Witztum, AH Lichtman - Annual Review of Pathology …, 2014 - annualreviews.org
Both the chronic development of atherosclerotic lesions and the acute changes in lesion
phenotype that lead to clinical cardiovascular events are significantly influenced by the …

Platelets in atherosclerosis

D Lievens, P von Hundelshausen - Thrombosis and …, 2011 - thieme-connect.com
Beyond obvious functions in haemostasis and thrombosis, platelets are considered to be
essential in proinflammatory surroundings such as atherosclerosis, allergy, rheumatoid …

The signaling role of CD40 ligand in platelet biology and in platelet component transfusion

C Aoui, A Prigent, C Sut, S Tariket… - International journal of …, 2014 - mdpi.com
The CD40 ligand (CD40L) is a transmembrane molecule of crucial interest in cell signaling
in innate and adaptive immunity. It is expressed by a variety of cells, but mainly by activated …