The emergence of one of the most recently described carbapenemases, namely, the New
Delhi metallo-lactamase (NDM-1), constitutes a critical and growingly important medical …

Carbapenem antibiotics are generally considered to be the most potent group of
antimicrobial agents with proven efficacy in the treatment of patients with severe bacterial …

Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

Carbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability
to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria …

The ascendancy of metallo-β-lactamases within the clinical sector, while not ubiquitous, has
nonetheless been dramatic; some reports indicate that nearly 30% of imipenem-resistant …

Optimal use of microbiology laboratories is essential to combat the spread of multiply
antibiotic-resistant pathogens. This is vital for patient care, as advocated by Jarvis in …

Rapid detection of metallo-β-lactamase (MBL)-producing gram-negative bacilli is necessary
to prevent their dissemination. The method using a disk with imipenem plus 750 μg of EDTA …

Carbapenemases may be defined as β-lactamases that significantly hydrolyze at least
imipenem or/and meropenem. Carbapenemases involved in acquired resistance are of …

Strains of Enterobacteriaceae producing an extended spectrum β‐lactamase have become
a concern in medical bacteriology as regards both antimicrobial treatment and infection …

Gram-negative bacilli with acquired metallo-β-lactamase (MBL) production have been
increasingly reported in some countries, necessitating their detection. The aim of this study …