Objective To update evidence‐based medicine recommendations for treating nonmotor
symptoms in Parkinson's disease (PD). Background The International Parkinson and …

Rapid eye movement (REM) sleep behaviour disorder (RBD) is a parasomnia that is
characterized by loss of muscle atonia during REM sleep (known as REM sleep without …

Importance Parkinson disease is the second most common neurodegenerative disease
worldwide. Although no available therapies alter the underlying neurodegenerative process …

Sleep disturbances are common in Parkinson's disease and comprise the entire spectrum of
sleep disorders. On the one hand regulation of sleep and wakefulness is affected in …

This systematic review provides supporting evidence for a clinical practice guideline for the
management of rapid eye movement (REM) sleep behavior disorder in adults and children …

Importance The dream enactment of rapid eye movement sleep behavior disorder (RBD) is
often the first indication of an impending α-synuclein disorder, such as Parkinson disease …

The central cholinergic system includes the basal forebrain nuclei, mainly projecting to the
cortex, the mesopontine tegmental nuclei, mainly projecting to the thalamus and subcortical …

Sleep disorders (SDs) are one of the most frequent non-motor symptoms of Parkinson's
disease (PD), usually increasing in frequency over the course of the disease and disability …

Parkinson's disease (PD) is an alpha-synucleinopathy that leads to prominent motor
symptoms including tremor, bradykinesia, and postural instability. Nonmotor symptoms …

Parkinson's disease (PD) is a complex, multisystem disorder with both neurologic and
systemic manifestations, which is usually associated with non-motor symptoms, including …