Childhood obesity has become major health concern for physicians, parents, and health
agencies around the world. Childhood obesity is associated with an increased risk for other …

Endothelial cells are both the source and target of factors contributing to atherosclerosis.
After the discovery of the endothelium-derived relaxing factor (EDRF) by Robert F. Furchgott …

Functional integrity of endothelial cells is an indicator and a prerequisite for vascular health
and counteracts the development of atherosclerosis. This concept of 'endothelial …

Vascular aging is a major risk factor for age-related cardiovascular diseases, which have
high rates of morbidity and mortality. It is characterized by changes in the blood vessels …

Since the beginning of the 20th century human life expectancy has doubled to more than 80
years, and growth and aging of the world population now represent major challenges for …

Aging is considered the most important nonmodifiable risk factor for cardiovascular disease
and death after age 28 years. Because of demographic changes the world population is …

The epithelial sodium channel is also expressed in vascular endothelium (endothelial
sodium channel [EnNaC]). Depending on ambient sodium concentration, EnNaC is …

As the world confronts the health challenges of an ageing population, there has been
dramatically increased interest in the science of ageing. This research has overwhelmingly …

Despite the clear-cut epidemiological evidence of protec-tive effects of endogenous
estrogens in premenopausal women, 1, 2 the results of randomized clinical trials using …

Diabetes and arterial hypertension continue to be the main causes of chronic renal failure in
2010, with a rising prevalence in part due to the worldwide obesity epidemic. Proteinuria is a …