[HTML][HTML] Arrhythmias in the COVID-19 patient

MP Lavelle, AD Desai, EY Wan - Heart Rhythm O2, 2022 - Elsevier
Coronavirus disease 2019 (COVID-19) has encompassed the globe since it was first
observed just under 2 years ago. Although the disease is predominantly a respiratory …

[HTML][HTML] Mechanism of COVID-19-induced cardiac damage from patient, in vitro and animal studies

EAV Jones - Current Heart Failure Reports, 2023 - Springer
Abstract Purpose of Review Though patient studies have been important for understanding
the disease, research done in animals and cell culture complement our knowledge from …

[HTML][HTML] SARS-CoV-2 spike protein-mediated cardiomyocyte fusion may contribute to increased arrhythmic risk in COVID-19

DJ Clemens, D Ye, W Zhou, CSJ Kim, DR Pease… - Plos one, 2023 - journals.plos.org
Background SARS-CoV-2-mediated COVID-19 may cause sudden cardiac death (SCD).
Factors contributing to this increased risk of potentially fatal arrhythmias include thrombosis …

[HTML][HTML] Signaling Pathways in Inflammation and Cardiovascular Diseases: An Update of Therapeutic Strategies

I Cucu - Immuno, 2022 - mdpi.com
Inflammatory processes represent a pivotal element in the development and complications
of cardiovascular diseases (CVDs). Targeting these processes can lead to the alleviation of …

[HTML][HTML] Activin a directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development

S MacDonnell, J Megna, Q Ruan, O Zhu… - Frontiers in …, 2022 - frontiersin.org
Activin A has been linked to cardiac dysfunction in aging and disease, with elevated
circulating levels found in patients with hypertension, atherosclerosis, and heart failure …

[HTML][HTML] Application of the pluripotent stem cells and genomics in cardiovascular research—what we have learnt and not learnt until now

M Simeon, S Dangwal, A Sachinidis, MX Doss - Cells, 2021 - mdpi.com
Personalized regenerative medicine and biomedical research have been galvanized and
revolutionized by human pluripotent stem cells in combination with recent advances in …

[HTML][HTML] Gq-Mediated Arrhythmogenic Signaling Promotes Atrial Fibrillation

F Hohendanner, A Prabhu, N Wilck, V Stangl, B Pieske… - Biomedicines, 2023 - mdpi.com
Background: Atrial fibrillation (AF) is promoted by various stimuli like angiotensin II,
endothelin-1, epinephrine/norepinephrine, vagal activation, or mechanical stress, all of …

[HTML][HTML] Application of hiPSC as a Drug Tester Via Mimicking a Personalized Mini Heart

L Wei, S Xia, Y Li, Y Qi, Y Wang, D Zhang, Y Hua… - Frontiers in …, 2022 - frontiersin.org
Human induced pluripotent stem cells (hIPSC) have been used to produce almost all types
of human cells currently, which makes them into several potential applications with …

Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19

D Ashok, T Liu, J Criscione, M Prakash, B Kim, J Chow… - bioRxiv, 2024 - biorxiv.org
Background Cardiac risk rises during acute SARS-CoV-2 infection and in long COVID
syndrome in humans, but the mechanisms behind COVID-19-linked arrhythmias are …

[HTML][HTML] SARS-CoV-2 infection in cardiovascular disease: Unmet need of stem cell models

LA Bors, B Orsolits, NM Ahmed, H Cho… - Physiology …, 2022 - akjournals.com
This review aims to summarise new approaches in SARS-CoV-2-related research in
cardiology. We provide a head-to-head comparison of models, such as animal research and …