[HTML][HTML] Present and future of metabolic and metabolomics studies focused on classical psychedelics in humans

F Madrid-Gambin, D Fabregat-Safont… - Biomedicine & …, 2023 - Elsevier
Psychedelics are classical hallucinogen drugs that induce a marked altered state of
consciousness. In recent years, there has been renewed attention to the possible use of …

Evaluating metabolite-based biomarkers for early diagnosis of pancreatic cancer: a systematic review

G Perazzoli, OM García-Valdeavero, M Pena, J Prados… - Metabolites, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with five-year
survival rates around 10%. The only curative option remains complete surgical resection, but …

Metabolomic analysis of pig spleen reveals African swine fever virus infection increased acylcarnitine levels to facilitate viral replication

X Yang, X Bie, H Liu, X Shi, D Zhang, DS Zhao… - Journal of …, 2023 - Am Soc Microbiol
African swine fever (ASF) is a devastating disease caused by the African swine fever virus
(ASFV) that adversely affects the pig industry. The spleen is the main target organ of ASFV; …

[HTML][HTML] Metabolomics analysis and diagnosis of lung cancer: insights from diverse sample types

S Liang, X Cao, Y Wang, P Leng, X Wen… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Lung cancer is a highly fatal disease that poses a significant global health burden. The
absence of characteristic clinical symptoms frequently results in the diagnosis of most …

Evaluation of two simultaneous metabolomic and proteomic extraction protocols assessed by ultra-high-performance liquid chromatography tandem mass …

RA Zenati, AD Giddey, HM Al-Hroub… - International Journal of …, 2023 - mdpi.com
Untargeted multi-omics analysis of plasma is an emerging tool for the identification of novel
biomarkers for evaluating disease prognosis, and for developing a better understanding of …

Exploring dynamic metabolome of the HepG2 cell line: rise and fall

OI Kiseleva, IY Kurbatov, VA Arzumanian, EV Ilgisonis… - Cells, 2022 - mdpi.com
Both biological and technical variations can discredit the reliability of obtained data in omics
studies. In this technical note, we investigated the effect of prolonged cultivation of the …

Mass spectrometric blood metabogram: acquisition, characterization, and prospects for application

PG Lokhov, EE Balashova, OP Trifonova… - International Journal of …, 2023 - mdpi.com
In metabolomics, many metabolites are measured simultaneously in a single run. Such
analytical performance opens up prospects for clinical laboratory diagnostics. In this work, a …

Optimization of a GC-MS method for the profiling of microbiota-dependent metabolites in blood samples: An application to type 2 diabetes and prediabetes

P Mojsak, K Maliszewska, P Klimaszewska… - Frontiers in Molecular …, 2022 - frontiersin.org
Changes in serum or plasma metabolome may reflect gut microbiota dysbiosis, which is also
known to occur in patients with prediabetes and type 2 diabetes (T2DM). Thus, developing a …

Therapeutic effect and mechanism of Anemarrhenae Rhizoma on Alzheimer's disease based on multi-platform metabolomics analyses

H Wang, JY Dai, YZ He, ZW Xia, XF Chen… - Frontiers in …, 2022 - frontiersin.org
Anemarrhenae Rhizoma (AR) has multiple pharmacological activities to prevent and treat
Alzheimer's disease (AD). However, the effect and its molecular mechanism are not …

Revealing novel biomarkers for diagnosing chronic kidney disease in pediatric patients

S Benito, N Unceta, M Maciejczyk… - Scientific Reports, 2024 - nature.com
Pediatric chronic kidney disease (CKD) is a clinical condition characterized by progressive
renal function deterioration. CKD diagnosis is based on glomerular filtration rate, but its …