[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | Is Melatonin the “Next Vitamin D”?: A Review of
Emerging Science, Clinical Uses, Safety, and Dietary Supplements Next Article in Journal …

[HTML][HTML] Dietary supplements in retinal diseases, glaucoma, and other ocular conditions

MC Medori, Z Naureen, K Dhuli, G Placidi… - Journal of Preventive …, 2022 - ncbi.nlm.nih.gov
Environmental pollution, inadequate eating habits and unhealthy lifestyles have led to a
tremendous increase in ocular diseases worldwide. Given the costly treatments that are …

Progressive retinal ganglion cell loss in primary open-angle glaucoma is associated with temperature circadian rhythm phase delay and compromised sleep

DG Gubin, ТN Malishevskaya… - Chronobiology …, 2019 - Taylor & Francis
Advanced primary open-angle glaucoma (POAG) is characterized by progressive retinal
ganglion cell complex (RGCC) damage that may cause subsequent disruption of the …

[HTML][HTML] Mechanisms behind retinal ganglion cell loss in diabetes and therapeutic approach

MC Potilinski, V Lorenc, S Perisset… - International Journal of …, 2020 - mdpi.com
Diabetes produces several changes in the body triggered by high glycemia. Some of these
changes include altered metabolism, structural changes in blood vessels and chronic …

[HTML][HTML] Therapeutic effects of melatonin on ocular diseases: knowledge map and perspective

H Yu, Q Wang, W Wu, W Zeng, Y Feng - Frontiers in Pharmacology, 2021 - frontiersin.org
Melatonin plays a critical role in the pathophysiological process including circadian rhythm,
apoptosis, and oxidative stress. It can be synthesized in ocular tissues, and its receptors are …

Melatonin as a modulator of degenerative and regenerative signaling pathways in injured retinal ganglion cells

KB Juybari, A Hosseinzadeh… - Current …, 2019 - ingentaconnect.com
Optic neuropathies refer to the dysfunction or degeneration of optic nerve fibers caused by
any reasons including ischemia, inflammation, trauma, tumor, mitochondrial dysfunction …

[HTML][HTML] The therapeutic trip of melatonin eye drops: from the ocular surface to the retina

D Rusciano, C Russo - Pharmaceuticals, 2024 - mdpi.com
Melatonin is a ubiquitous molecule found in living organisms, ranging from bacteria to plants
and mammals. It possesses various properties, partly due to its robust antioxidant nature …

Arylalkylamine N‐acetyltransferase (AANAT): Blue light induction, nuclear translocation, and potential role in the survival of chicken retina neuronal cells

MN Rios, NA Marchese… - Journal of Pineal Research, 2023 - Wiley Online Library
In vertebrates, arylalkylamine N‐acetyltransferase (AANAT; EC 2.3. 1.87) is the time‐
keeping and key regulatory enzyme in melatonin (Mel) biosynthesis. AANAT is present in …

Melatonin: implications for ocular disease and therapeutic potential

L Scuderi, S Davinelli, CM Iodice… - Current …, 2019 - ingentaconnect.com
Melatonin, an indoleamine secreted mainly by the pineal gland, is known to modulate a
wide range of circadian functions. However, this neurohormone is also synthesized within …

[HTML][HTML] Short-Wavelength Light–Blocking Filters and Oral Melatonin Administration in Patients With Retinitis Pigmentosa: Protocol for a Randomized Controlled Trial

S Pastor-Idoate, M Mateos-Olivares… - JMIR Research …, 2023 - researchprotocols.org
Background The medical community is beginning to recognize that retinitis pigmentosa
(RP), due to its disabling progression, eventually leads to a reduction in the patient´ s quality …