For over two decades, the minority stress model has guided research on the health of
sexually-diverse individuals (those who are not exclusively heterosexual) and gender …

Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Abstract Adverse Childhood Experiences (ACEs) are stressful and/or traumatic experiences
associated with an increased lifetime risk of negative health outcomes. The Allostatic Load …

BackgroundSouth Africa's national lockdown introduced serious threats to public mental
health in a society where one in three individuals develops a psychiatric disorder during …

Classic theories of stress and health are largely based on assumptions regarding how
different psychosocial stressors influence biological processes that, in turn, affect human …

Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Given the high prevalence and burden of mental disorders, fostering the understanding of
protective factors is an urgent issue for translational medicine in psychiatry. The concept of …

Adverse childhood experiences (ACEs) are associated with poor future mental and physical
health. Altered biological reactivity to mental stress may be a possible mechanism linking …

Social isolation and discrimination are growing public health concerns associated with poor
physical and mental health. They are risk factors for increased morbidity and mortality and …