Control of Lactose Transport, β-Galactosidase Activity, and Glycolysis by CcpA in Streptococcus thermophilus: Evidence for Carbon Catabolite Repression by a Non …

PTC van den Bogaard, M Kleerebezem… - Journal of …, 2000 - Am Soc Microbiol
Streptococcus thermophilus, unlike many other gram-positive bacteria, prefers lactose over
glucose as the primary carbon and energy source. Moreover, lactose is not taken up by a …

Binding of the catabolite repressor protein CcpA to its DNA target is regulated by phosphorylation of its corepressor HPr

BE Jones, V Dossonnet, E Kuster, W Hillen… - Journal of Biological …, 1997 - ASBMB
Catabolite repression of a number of catabolic operons in bacilli is mediated by the
catabolite control protein CcpA, the phosphocarrier protein HPr from the …

Elaborate transcription regulation of the Bacillus subtilis ilv‐leu operon involved in the biosynthesis of branched‐chain amino acids through global regulators of CcpA …

S Tojo, T Satomura, K Morisaki… - Molecular …, 2005 - Wiley Online Library
The Bacillus subtilis ilv‐leu operon involved in the biosynthesis of branched‐chain amino
acids is under negative regulation mediated by TnrA and CodY, which recognize and bind to …

Catabolite Regulation of the pta Gene as Part of Carbon Flow Pathways in Bacillus subtilis

E Presecan-Siedel, A Galinier, R Longin… - Journal of …, 1999 - Am Soc Microbiol
In Bacillus subtilis, the products of the pta and ackA genes, phosphotransacetylase and
acetate kinase, play a crucial role in the production of acetate, one of the most abundant by …

Catabolite Repression and Activation in Bacillus subtilis: Dependency on CcpA, HPr, and HprK

GL Lorca, YJ Chung, RD Barabote, W Weyler… - Journal of …, 2005 - Am Soc Microbiol
Previous studies have suggested that the transcription factor CcpA, as well as the
coeffectors HPr and Crh, both phosphorylated by the HprK kinase/phosphorylase, are …

A flexible partnership: the CytR anti‐activator and the cAMP–CRP activator protein, comrades in transcription control

P Valentin‐Hansen, L Søgaard‐Andersen… - Molecular …, 1996 - Wiley Online Library
A vital point in gene regulation is control at the level of transcription initiation. Recent
research has established that this regulation can involve sophisticated networks of …

Positive regulation of Bacillus subtilis ackA by CodY and CcpA: establishing a potential hierarchy in carbon flow

RP Shivers, SS Dineen… - Molecular …, 2006 - Wiley Online Library
Conversion of pyruvate to acetate via the phosphotransacetylase‐acetate kinase pathway
generates ATP and is a major overflow pathway under conditions of carbon and nitrogen …

The HPr kinase from Bacillus subtilis is a homo-oligomeric enzyme which exhibits strong positive cooperativity for nucleotide and fructose 1, 6-bisphosphate binding

JM Jault, S Fieulaine, S Nessler, P Gonzalo… - Journal of Biological …, 2000 - ASBMB
Carbon catabolite repression allows bacteria to rapidly alter the expression of catabolic
genes in response to the availability of metabolizable carbon sources. In Bacillus subtilis …

High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

BC Marciniak, M Pabijaniak, A de Jong, R Dűhring… - BMC genomics, 2012 - Springer
Abstract Background In Bacillus subtilis and its relatives carbon catabolite control, a
mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism …

Transcriptional analysis of catabolite repression in Clostridium acetobutylicum growing on mixtures of D-glucose and D-xylose

C Grimmler, C Held, W Liebl, A Ehrenreich - Journal of biotechnology, 2010 - Elsevier
Clostridium acetobutylicum is a strict anaerobic organism that is used for biotechnological
butanol fermentation. It ferments various hexoses and pentoses to solvents but prefers …