Innate immunity in protection and pathogenesis during coronavirus infections and COVID-19
RKS Malireddi, BR Sharma… - Annual Review of …, 2024 - annualreviews.org
The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …
Potential convergence of olfactory dysfunction in Parkinson's disease and COVID-19: The role of neuroinflammation
H Li, J Qian, Y Wang, J Wang, X Mi, L Qu… - Ageing Research …, 2024 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder that affects 7-10 million
individuals worldwide. A common early symptom of PD is olfactory dysfunction (OD), and …
individuals worldwide. A common early symptom of PD is olfactory dysfunction (OD), and …
SARS-CoV-2 envelope protein induces necroptosis and mediates inflammatory response in lung and colon cells through receptor interacting protein kinase 1
Abstract SARS-CoV-2 Envelope protein (E) is one of the crucial components in virus
assembly and pathogenesis. The current study investigated its role in the SARS-CoV-2 …
assembly and pathogenesis. The current study investigated its role in the SARS-CoV-2 …
Multifaceted role of SARS-CoV-2 structural proteins in lung injury
G Zheng, G Qiu, H Qian, Q Shu, J Xu - Frontiers in Immunology, 2024 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third human
coronavirus to cause acute respiratory distress syndrome (ARDS) and contains four …
coronavirus to cause acute respiratory distress syndrome (ARDS) and contains four …
IL-6 from cerebrospinal fluid causes widespread pain via STAT3-mediated astrocytosis in chronic constriction injury of the infraorbital nerve
N Yu, H Cui, S Jin, P Liu, Y Fang, F Sun, Y Cao… - Journal of …, 2024 - Springer
Background The spinal inflammatory signal often spreads to distant segments, accompanied
by widespread pain symptom under neuropathological conditions. Multiple cytokines are …
by widespread pain symptom under neuropathological conditions. Multiple cytokines are …
From Immunity to Neurogenesis: Toll-like Receptors as Versatile Regulators in the Nervous System
DM Abarca-Merlin, JA Martínez-Durán… - International Journal of …, 2024 - mdpi.com
Toll-like receptors (TLRs) are among the main components of the innate immune system.
They can detect conserved structures in microorganisms and molecules associated with …
They can detect conserved structures in microorganisms and molecules associated with …
SARS-CoV-2 Omicron Variants Show Attenuated Neurovirulence Compared with the Wild-Type Strain in Elderly Human Brain Spheroids
W Chen, X Jiang, W Liang, H Bai, M Xu, Z Liu, L Yi… - Research, 2024 - spj.science.org
Infection with severe acute respiratory syndrome coronavirus 2 Omicron variants still causes
neurological complications in elderly individuals. However, whether and how aging brains …
neurological complications in elderly individuals. However, whether and how aging brains …
Interactome screening of Human Cytomegalovirus and the Complement system & Investigating the pre-clinical immunogenicity of a novel SARS-CoV-2 Envelope (E) …
EL Lujan - 2023 - escholarship.org
Human Cytomegalovirus (HCMV) is a ubiquitous virus that is a leading cause of both
congenital infections in neonates and opportunistic infections in immunodeficient persons …
congenital infections in neonates and opportunistic infections in immunodeficient persons …
The Multifaceted and Paradoxical Roles of Toll-Like Receptors and Their Signaling Adaptors in Modulating Microglia Innate Immune Response to Neurotropic …
E Davis - 2024 - search.proquest.com
Despite recent advances in medicine, viral infections of the central nervous system (CNS)
constitute 20% of diagnosed neurological disorders. Left untreated, these infections can …
constitute 20% of diagnosed neurological disorders. Left untreated, these infections can …