Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

A growing body of research demonstrates that psychosocial factors play an important role in
the development of hypertension. Previous reviews have identified several key factors (ie …

Background Parental absence in childhood has been associated with multiple negative
consequences, such as depression and anxiety in young adulthood. Objective To assess …

Background Removal from family of origin to state care can be a highly challenging
childhood experience and is itself linked to an array of unfavourable outcomes in adult life …

Objective Identifying the life course health effects of childhood adversity is a burgeoning
area of research, particularly in relation to cardiovascular disease (CVD). However …

Objectives Severe early life stress (ELS) is a well‐known risk factor for mental health
disorders later in life. Not only mental health disorders are affected by ELS but early life …

We examined the effects of early life stress on cognitive ability and decline among men of
the Helsinki Birth Cohort Study, 10% of whom were separated temporarily (mean age at …

Background Severe stress experienced in early life may have long-term effects on adult
physiological and psychological health and well-being. We studied physical and …

Early-life stress (ELS) is known to be associated with an increased risk of neuropsychiatric
and cardiometabolic disease in later life. One of the potential mechanisms underpinning this …

Adverse childhood experiences (ACEs), defined as traumatic events in childhood that range
from various forms of abuse to household challenges and dysfunction, have devastating …