Microbial cell factories have been used for the production of valuable chemical compounds
using a classical metabolic engineering approach, but this requires much time and cost, and …

Constraint-based modeling (CBM) has evolved as the core systems biology tool to map the
interrelations between genotype, phenotype, and external environment. The recent …

The biorefinery concept holds the promise of green industrial production of biofuel or
chemicals, in which fossil resources are substituted by renewable biomass, securing …

This study evaluated the ability to accumulate biomass and lipids during the autotrophic
culture of four Colombian-native microalgae strains (Scenedesmus ovalternus …

Streptomyces clavuligerus (S. clavuligerus) is a filamentous Gram-positive bacterial
producer of the β-lactamase inhibitor clavulanic acid (CA). Antibiotics biosynthesis and …

To study the relationship between the yield of 1, 3‐propanediol (1, 3‐PDO) and the flux
change of the Clostridium butyricum metabolic pathway, an optimized calculation method …

Computational modeling and simulation of biological systems have become valuable tools
for understanding and predicting cellular performance and phenotype generation. This work …

Metabolic engineering principles have long been applied to explore the metabolic networks
of complex microbial cell factories under a variety of environmental constraints for effective …

Living organisms in analogy with chemical factories use simple molecules such as sugars to
produce a variety of compounds which are necessary for sustaining life and some of which …

Crude glycerol can serve as a low-cost substrate in biotechnological applications.
Electrofermentation is a bioelectrochemical technology in which it is possible to improve and …