HIV infection

LG Bekker, C Beyrer, N Mgodi, SR Lewin… - Nature Reviews …, 2023 - nature.com
The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …

Chytrid fungi and global amphibian declines

MC Fisher, TWJ Garner - Nature Reviews Microbiology, 2020 - nature.com
Discovering that chytrid fungi cause chytridiomycosis in amphibians represented a paradigm
shift in our understanding of how emerging infectious diseases contribute to global patterns …

Timing the SARS-CoV-2 index case in Hubei province

J Pekar, M Worobey, N Moshiri, K Scheffler… - Science, 2021 - science.org
Understanding when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
emerged is critical to evaluating our current approach to monitoring novel zoonotic …

The early spread and epidemic ignition of HIV-1 in human populations

NR Faria, A Rambaut, MA Suchard, G Baele, T Bedford… - science, 2014 - science.org
Thirty years after the discovery of HIV-1, the early transmission, dissemination, and
establishment of the virus in human populations remain unclear. Using statistical …

[图书][B] Bayesian evolutionary analysis with BEAST

AJ Drummond, RR Bouckaert - 2015 - books.google.com
What are the models used in phylogenetic analysis and what exactly is involved in Bayesian
evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you …

Origins of HIV and the AIDS pandemic

PM Sharp, BH Hahn - Cold Spring …, 2011 - perspectivesinmedicine.cshlp.org
Acquired immunodeficiency syndrome (AIDS) of humans is caused by two lentiviruses,
human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2). Here, we describe the …

A highly virulent variant of HIV-1 circulating in the Netherlands

C Wymant, D Bezemer, F Blanquart, L Ferretti, A Gall… - Science, 2022 - science.org
We discovered a highly virulent variant of subtype-B HIV-1 in the Netherlands. One hundred
nine individuals with this variant had a 0.54 to 0.74 log10 increase (ie, a~ 3.5-fold to 5.5-fold …

Improving the accuracy of demographic and molecular clock model comparison while accommodating phylogenetic uncertainty

G Baele, P Lemey, T Bedford, A Rambaut… - Molecular biology …, 2012 - academic.oup.com
Recent developments in marginal likelihood estimation for model selection in the field of
Bayesian phylogenetics and molecular evolution have emphasized the poor performance of …

Natural selection and infectious disease in human populations

EK Karlsson, DP Kwiatkowski, PC Sabeti - Nature Reviews Genetics, 2014 - nature.com
The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens

W Fischer, EE Giorgi, S Chakraborty, K Nguyen… - Cell host & …, 2021 - cell.com
Humanity is currently facing the challenge of two devastating pandemics caused by two very
different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which …