There has been a steep increase in allergic and autoimmune diseases, reaching epidemic
proportions and now affecting more than one billion people worldwide. These diseases are …

Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic
feature is persistent itching of the skin. The chronic, relapsing course of the disease …

There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …

Lipid synthesis is necessary for formation of epithelial barriers and homeostasis with
external microbes. An analysis of the response of human keratinocytes to several different …

Atopic dermatitis (AD) is a common inflammatory skin disorder characterized by recurrent
eczematous lesions and intense itch. Although it most often starts in infancy and affects …

Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a
large number of mammals. In humans, L. reuteri is found in different body sites, including the …

Atopic dermatitis (AD) is a common and relapsing skin disease that is characterized by skin
barrier dysfunction, inflammation, and chronic pruritus. While AD was previously thought to …

The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both
after atopic dermatitis (AD) onset. Mechanisms for developing atopic comorbidities after AD …