Tumor cell membrane‐based vaccines: a potential boost for cancer immunotherapy

M Yang, J Zhou, L Lu, D Deng, J Huang, Z Tang… - …, 2024 - Wiley Online Library
Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with
relatively low toxicity, they have long been considered for application in repressing cancer …

Autophagy-amplifying nanoparticles evoke immunogenic cell death combined with anti-PD-1/PD-L1 for residual tumors immunotherapy after RFA

S Zhang, Y Huang, S Pi, H Chen, F Ye, C Wu… - Journal of …, 2023 - Springer
Incomplete radiofrequency ablation (IRFA) triggers mild protective autophagy in residual
tumor cells and results in an immunosuppressive microenvironment. This accelerates the …

Cell death shapes cancer immunity: spotlighting PANoptosis

L Gao, C Shay, Y Teng - Journal of Experimental & Clinical Cancer …, 2024 - Springer
PANoptosis represents a novel type of programmed cell death (PCD) with distinctive
features that incorporate elements of pyroptosis, apoptosis, and necroptosis. PANoptosis is …

Self‐Cascade Nanozyme Reactor as a Cuproptosis Inducer Synergistic Inhibition of Cellular Respiration Boosting Radioimmunotherapy

R Li, W Zhao, Z Han, N Feng, T Wu, H Xiong, W Jiang - Small, 2024 - Wiley Online Library
Intrinsic or acquired radioresistance remained an important challenge in the successful
management of cancer. Herein, a novel “smart” multifunctional copper‐based …

Radiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of …

J Jiao, Y Zhang, W Zhang, M He, M Meng… - Acta Pharmacologica …, 2024 - nature.com
Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor
progression and immunotherapy resistance. Priming the tumor immune microenvironment …

Enhancing cancer immunotherapy with photodynamic therapy and nanoparticle: making tumor microenvironment hotter to make immunotherapeutic work better

J Thiruppathi, V Vijayan, IK Park, SE Lee… - Frontiers in …, 2024 - frontiersin.org
Cancer immunotherapy has made tremendous advancements in treating various
malignancies. The biggest hurdle to successful immunotherapy would be the …

Emerging role of immunogenic cell death in cancer immunotherapy: Advancing next-generation CAR-T cell immunotherapy by combination

Z Zhou, Y Mai, G Zhang, Y Wang, P Sun, Z Jing, Z Li… - Cancer Letters, 2024 - Elsevier
Immunogenic cell death (ICD) is a stress-driven form of regulated cell death (RCD) in which
dying tumor cells' specific signaling pathways are activated to release damage-associated …

Immune modulatory roles of radioimmunotherapy: biological principles and clinical prospects

X Wang, Y Wang, Y Zhang, H Shi, K Liu… - Frontiers in …, 2024 - frontiersin.org
Radiation therapy (RT) not only can directly kill tumor cells by causing DNA double-strand
break, but also exerts anti-tumor effects through modulating local and systemic immune …

Peripheral Blood CD8+ T-Lymphocyte Subsets Are Associated with Prognosis in Prostate Cancer Patients

CN Baxevanis, S Stokidis, M Goulielmaki, AD Gritzapis… - Onco, 2023 - mdpi.com
Simple Summary The field of precision oncology may benefit from the discovery of reliable
biomarkers for prognosis and prediction, which will help to tailor therapeutic treatments, thus …

From pre-clinical to translational brain metastasis research: current challenges and emerging opportunities

E Aleksandrovic, S Zhang, D Yu - Clinical & Experimental Metastasis, 2024 - Springer
Brain metastasis, characterized by poor clinical outcomes, is a devastating disease. Despite
significant mechanistic and therapeutic advances in recent years, pivotal improvements in …