To mimic the structure of breast tumor microenvironment, novel double-network poly (N ɛ-
acryloyl l-lysine)/hyaluronic acid (pLysAAm/HA) hydrogels were fabricated by a two-step …

The intricate microenvironment in which malignant cells reside is essential for the
progression of tumor growth. Both the physical and biochemical features of the tumor …

The cancer stem cell (CSC) population displays self-renewal capabilities, resistance to
conventional therapies, and a tendency to post-treatment recurrence. Increasing knowledge …

Cancer stem cells (CSCs) are potential platforms to high-throughput screen anti-cancer
drugs. However, they are difficult to isolate from cancer cells. Therefore, we proposed to …

Breast cancer stem cells (BCSCs) are tumor-initiating cells responsible for metastasis and
tumor reappearance, but their research is limited by the impossibility to cultivate them in a …

During anticancer drug development, most compounds selected by in vitro screening are
ineffective in in vivo studies and clinical trials due to the unreliability of two-dimensional (2D) …

Two-dimensional cell culturing has proven inadequate as a reliable preclinical tumour
model due to many inherent limitations. Hence, novel three-dimensional (3D) cell culture …

Cancer stem cells (CSCs) are most likely the reason of cancer reoccurrence and metastasis.
For further elucidation of the mechanism underlying the characteristics of CSCs, it is …

Open-source 3D printers mean objects can be quickly and efficiently produced. However,
design and fabrication parameters need to be optimized to set up the correct printing …

Despite advances in cancer treatment, breast cancer remains the second foremost cause of
cancer mortality among women, with a high rate of relapse after initial treatment success. A …