Recent studies have suggested that microenvironmental stimuli play a significant role in
regulating cellular proliferation and migration, as well as in modulating self-renewal and …

Breast cancer (BC) and ovarian cancer (OC) are among the most common and deadly
cancers affecting women worldwide. Both are complex diseases with marked heterogeneity …

The nanomaterial with the novel biologically active compounds has been actively
investigated for application in cancer research. Substantial use of nanofibrous scaffold for …

Goal: Artificially engineering the tumor microenvironment in vitro as a vital tool for
understanding the mechanism of tumor progression. In this study, we developed three …

Abstract Two-dimensional (2D) cell culture structures are demonstrated to differ from the in
vivo environment. Therefore, cells adopt a flattened morphology that may lead to a non …

Abstract Two-dimensional (2D) culturing of cancer cells has been indispensable for the
development of anti-cancer drugs. Drug development, however, is lengthy and costly with a …

Three-dimensional (3D) customized scaffolds are anticipated to provide new frontiers in cell
manipulation and advanced therapy methods. Here, we demonstrate the application of …

An important aim of tissue engineering is to design biomimetic materials with specific cell
binding motifs and precisely controlled structural organization, thereby providing …

Only a small cell population of a breast tumour presents stem cell characteristics, thus so-
called breast cancer stem cells (BCSCs). BCSCs are tumour-initiating cells and …

The continuous development of simple and practical cell cryopreservation methods is of
great importance to a variety of sectors, especially when considering the efficient short‐and …