Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

Long covid—mechanisms, risk factors, and management

H Crook, S Raza, J Nowell, M Young, P Edison - bmj, 2021 - bmj.com
Since its emergence in Wuhan, China, covid-19 has spread and had a profound effect on
the lives and health of people around the globe. As of 4 July 2021, more than 183 million …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), which began in Wuhan, China, in
December 2019, has caused a large global pandemic and poses a serious threat to public …

NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

The role of oxidative stress in the pathogenesis of infections with coronaviruses

C Gain, S Song, T Angtuaco, S Satta… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

Potential therapeutic targets and vaccine development for SARS-CoV-2/COVID-19 pandemic management: a review on the recent update

U Anand, S Jakhmola, O Indari, HC Jha… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly pathogenic
novel virus that has caused a massive pandemic called coronavirus disease 2019 (COVID …

Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

C Tindle, MK Fuller, A Fonseca, S Taheri… - Elife, 2021 - elifesciences.org
Background: SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage
in the lungs in the setting of an overzealous immune response whose origin remains …

Significance of NETs formation in COVID-19

K Janiuk, E Jabłońska, M Garley - Cells, 2021 - mdpi.com
Severe contagious respiratory disease—COVID-19—caused by the SARS-CoV-2
coronavirus, can lead to fatal respiratory failure associated with an excessive inflammatory …

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …

Ivermectin shows clinical benefits in mild to moderate COVID19: a randomized controlled double-blind, dose-response study in Lagos

OE Babalola, CO Bode, AA Ajayi… - … Journal of Medicine, 2021 - academic.oup.com
Introduction In vitro studies have shown the efficacy of Ivermectin (IV) to inhibit the SARS—
CoV-2 viral replication, but questions remained as to in-vivo applications. We set out to …