Cerebral organoids—challenges to establish a brain prototype

AV Eremeev, OS Lebedeva, ME Bogomiakova… - Cells, 2021 - mdpi.com
The new cellular models based on neural cells differentiated from induced pluripotent stem
cells have greatly enhanced our understanding of human nervous system development …

OrgaQuant: human intestinal organoid localization and quantification using deep convolutional neural networks

T Kassis, V Hernandez-Gordillo, R Langer… - Scientific reports, 2019 - nature.com
Organoid cultures are proving to be powerful in vitro models that closely mimic the cellular
constituents of their native tissue. Organoids are typically expanded and cultured in a 3D …

Responsible use of organoids in precision medicine: the need for active participant involvement

MA Lensink, KR Jongsma, SN Boers… - …, 2020 - journals.biologists.com
Organoids are three-dimensional multicellular structures grown in vitro from stem cells and
which recapitulate some organ function. They are derivatives of living tissue that can be …

Mini-gut feelings: perspectives of people with cystic fibrosis on the ethics and governance of organoid biobanking

MA Lensink, SN Boers, VA M Gulmans… - Personalized …, 2021 - Taylor & Francis
Aim: Organoid technology has enormous potential for precision medicine, such as has
recently been demonstrated in the field of cystic fibrosis. However, storage and use of …

[HTML][HTML] Landscape of human organoids: Ideal model in clinics and research

X Han, C Cai, W Deng, Y Shi, L Li, C Wang… - The …, 2024 - ncbi.nlm.nih.gov
In the last decade, organoid research has entered a golden era, signifying a pivotal shift in
the biomedical landscape. The year 2023 marked a milestone with the publication of …

Initial designs of artificial humans: intellectual property and ethical aspects

R Budnik, A Tedeev - Law, Innovation and Technology, 2023 - Taylor & Francis
Startups and tech giants, working on the computer replication of human personality, are
showing remarkable progress. A substantial part of this activity concentrates on the …

Ergonomic constraints for astronauts: challenges and opportunities today and for the future

M Braddock, K Szocik, R Campa - 2019 - ruj.uj.edu.pl
Manned spaceflight is ergonomically constrained by living and working in a confined space
in microgravity where astronauts on both short and long duration missions are exposed to …

An artificial nervous system to treat chronic stroke

MD Serruya, RH Rosenwasser - Artificial Organs, 2021 - Wiley Online Library
Despite remarkable advances in the treatment of numerous medical conditions, neurological
disease and injury remains an outstanding challenge and cause of disability worldwide. The …

[PDF][PDF] Substrate independence, migration, and the naturalistic attitude

M Atkinson III - Living and thinking in the postdigital world. Theories …, 2021 - academia.edu
This paper argues that the transhumanist dream of whole brain emulation and migration of
human consciousness from one substrate to another suffers upon phenomenological …

Singularity's potential for sustainability and environmental health and well-being

D Courard-Hauri - Good Health and Well-Being, 2020 - Springer
Sustainable Development Goal 3 (SDG3) pledges to “Ensure healthy lives and promote well-
being for all at all ages”(UN 2015a). Health is affected by multitude of factors, inherent to …