More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

IL‐37 is unique in the IL‐1 family in that unlike other members of the family, IL‐37 broadly
suppresses innate immunity. IL‐37 can be elevated in humans with inflammatory and …

IL-37, a new member of the IL-1 cytokine family, is a natural inhibitor of innate immunity
associated with autoimmune diseases. This study was undertaken to evaluate whether IL-37 …

Background The aim of this study was to assess interleukin (IL)-37 production in asthmatic
children in serum and induced sputum and to look to the impact of IL-37 on pro-inflammatory …

Interleukin (IL)-37 and IL-33 are among the latest cytokines identified, playing a role in
several inflammatory conditions, spanning from systemic conditions to tumors to localized …

Autoimmune diseases are characterized by the impaired function and the destruction of
tissues that are caused by an immune response in which aberrant antibodies are generated …

Autoimmune diseases (AIDs) are characterized by dysfunction and tissue destruction, and
recent studies have shown that interleukin (IL)‑37 expression is dysregulated in AIDs …

IL-37 was discovered as an anti-inflammatory and immunosuppressive cytokine of the IL-1
family. Significant advancements in the understanding of signaling pathways associated …

Cartilage has a limited healing capacity; however, studies into the basic biological
characteristics, formation and structural maintenance of the cartilage collagen network are …