Stroke is a leading cause of death and disability world-widely. The incidence rate of stroke
has been increasing due to the aging population and lifestyle changes. At present, the only …

Stroke is ranked as the second leading cause of death worldwide and a major cause of long-
term disability. A potential therapeutic target that could offer favorable outcomes in stroke is …

Background Restoration of brain tissue perfusion is a determining factor in the neurological
evolution of patients with traumatic brain injury (TBI) and hemorrhagic shock (HS). In a …

Stroke is a highly lethal and disabling disease of the central nervous system exacerbated by
oxidative stress, inflammation, and ferroptosis. However, the blood–brain barrier makes it …

The aging of the global population poses significant scientific challenges. Moreover, the
biological process of aging is the most significant risk factor for most chronic illnesses; …

Background Inflammation may mediate response to acute reperfusion therapy (RT) in acute
cerebral ischaemia. Neutrophil-lymphocyte ratio (NLR), an inflammatory biomarker, may …

Regardless of the progress made in the pathogenesis of ischemic stroke, it remains a
leading cause of adult disability and death. To date, the most effective treatment for ischemic …

In vitro and preclinical in vivo research in the last 35 years has clearly highlighted the crucial
physiopathological role of glial cells, namely astrocytes/microglia/oligodendrocytes and …

Ischemic stroke leads to neuronal damage and severe inflammation that activate iNOS
expression in different cell types, especially inflammatory cells in the brain. It is shown that …

Background Ischemic stroke is the leading cause of disability worldwide. Long noncoding
RNAs (lncRNAs) play important roles in the pathogenesis of cerebral ischemia. This study …