Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation,
autoimmune diseases, and cancer. To exert their broad physiological and therapeutic …

Advances in technology have allowed for the sensitive, specific, and simultaneous
quantitative profiling of steroid precursors, bioactive steroids and inactive metabolites …

Background The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin),
receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1 …

The production of plastic products, which requires phthalate plasticizers, has resulted in the
problems for human health, especially that of reproductive health. Phthalate exposure can …

Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …

Recent evidence has revealed anti-inflammatory properties of vitamin D as well as extra-
skeletal activity. In this context, vitamin D seems to be involved in infections, autoimmune …

Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …

In the circulation, testosterone and other sex hormones are bound to binding proteins, which
play an important role in regulating their transport, distribution, metabolism, and biological …

The gut microbiota is a complex and dynamic ecosystem essential for the proper functioning
of the organism, affecting the health and disease status of the individuals. There is …

Comprehensive, high throughput analysis of the plasma proteome has the potential to
enable holistic analysis of the health state of an individual. Based on our own experience …