Retinopathy of prematurity

A Hellström, LEH Smith, O Dammann - The lancet, 2013 - thelancet.com
The immature retinas of preterm neonates are susceptible to insults that disrupt
neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors …

Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)

ASH Tsai, HD Chou, XC Ling, T Al-Khaled… - Progress in retinal and …, 2022 - Elsevier
The incidence of retinopathy of prematurity (ROP) continues to rise due to the improved
survival of very low birth weight infants in developed countries. This epidemic is also fueled …

Wnt Signaling in vascular eye diseases

Z Wang, CH Liu, S Huang, J Chen - Progress in retinal and eye research, 2019 - Elsevier
The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …

Pathophysiology, screening and treatment of ROP: a multi-disciplinary perspective

T Chan-Ling, GA Gole, GE Quinn, SJ Adamson… - Progress in retinal and …, 2018 - Elsevier
The population of infants at risk for retinopathy of prematurity (ROP) varies by world region;
in countries with well developed neonatal intensive care services, the highest risk infants are …

Ischemic retinopathies: oxidative stress and inflammation

JC Rivera, R Dabouz, B Noueihed… - Oxidative medicine …, 2017 - Wiley Online Library
Ischemic retinopathies (IRs), such as retinopathy of prematurity (ROP), diabetic retinopathy
(DR), and (in many cases) age‐related macular degeneration (AMD), are ocular disorders …

[HTML][HTML] Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies

JC Rivera, M Holm, D Austeng, TS Morken… - Journal of …, 2017 - Springer
Retinopathy of prematurity (ROP) is an important cause of childhood blindness globally, and
the incidence is rising. The disease is characterized by initial arrested retinal vascularization …

Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A

JS Joyal, N Sitaras, F Binet, JC Rivera… - Blood, The Journal …, 2011 - ashpublications.org
The failure of blood vessels to revascularize ischemic neural tissue represents a significant
challenge for vascular biology. Examples include proliferative retinopathies (PRs) such as …

Roles of exosomes in ocular diseases

J Liu, F Jiang, Y Jiang, Y Wang, Z Li, X Shi… - International journal …, 2020 - Taylor & Francis
Exosomes, nanoscale vesicles with a diameter of 30 to 150 nm, are composed of a lipid
bilayer, protein, and genetic material. Exosomes are secreted by virtually all types of cells in …

The role of glia in retinal vascular disease

NJ Coorey, W Shen, SH Chung, L Zhu… - Clinical and …, 2012 - Taylor & Francis
Retinal vascular diseases collectively represent a leading cause of blindness.
Unsurprisingly, pathological characterisation and treatment of retinal 'vascular'diseases …

The renin–angiotensin system in retinal health and disease: its influence on neurons, glia and the vasculature

EL Fletcher, JA Phipps, MM Ward, KA Vessey… - Progress in retinal and …, 2010 - Elsevier
Renin–Angiotensin System is classically recognized for its role in the control of systemic
blood pressure. However, the retina is recognized to have all the components necessary for …