The renin–angiotensin system in retinal health and disease: its influence on neurons, glia and the vasculature

EL Fletcher, JA Phipps, MM Ward, KA Vessey… - Progress in retinal and …, 2010 - Elsevier
Renin–Angiotensin System is classically recognized for its role in the control of systemic
blood pressure. However, the retina is recognized to have all the components necessary for …

Insights into the developing fovea revealed by imaging

Y He, X Chen, I Tsui, L Vajzovic, SR Sadda - Progress in Retinal and Eye …, 2022 - Elsevier
Early development of the fovea has been documented by histological studies over the past
few decades. However, structural distortion due to sample processing and the paucity of …

The neural retina in retinopathy of prematurity

RM Hansen, A Moskowitz, JD Akula… - Progress in retinal and eye …, 2017 - Elsevier
Retinopathy of prematurity (ROP) is a neurovascular disease that affects prematurely born
infants and is known to have significant long term effects on vision. We conducted the …

Decoupling oxygen tension from retinal vascularization as a new perspective for management of retinopathy of prematurity. New opportunities from β-adrenoceptors

L Filippi, M Cammalleri, R Amato, M Ciantelli… - Frontiers in …, 2022 - frontiersin.org
Retinopathy of prematurity (ROP) is an evolutive and potentially blinding eye disease that
affects preterm newborns. Unfortunately, until now no conservative therapy of active ROP …

Arginase in retinopathy

SP Narayanan, M Rojas, J Suwanpradid… - Progress in retinal and …, 2013 - Elsevier
Ischemic retinopathies, such as diabetic retinopathy (DR), retinopathy of prematurity and
retinal vein occlusion are a major cause of blindness in developed nations worldwide. Each …

Exosomes from microglia attenuate photoreceptor injury and neovascularization in an animal model of retinopathy of prematurity

W Xu, Y Wu, Z Hu, L Sun, G Dou, Z Zhang… - … Therapy-Nucleic Acids, 2019 - cell.com
The role of microglia in the pathophysiology of ischemic retinal diseases has been studied
extensively. Exosomes from microglial cells exert protective effects during several nervous …

Characterization of retinal function and glial cell response in a mouse model of oxygen‐induced retinopathy

KA Vessey, JL Wilkinson‐Berka… - Journal of Comparative …, 2011 - Wiley Online Library
Retinal neovascularization, such as that occurring in proliferative diabetic retinopathy and
retinopathy of prematurity, can have serious effects on visual function. By using a mouse …

Automated diagnosis of plus disease in retinopathy of prematurity using quantification of vessels characteristics

SM Sharafi, N Ebrahimiadib, R Roohipourmoallai… - Scientific Reports, 2024 - nature.com
The condition known as Plus disease is distinguished by atypical alterations in the retinal
vasculature of neonates born prematurely. It has been demonstrated that the diagnosis of …

Antiangiogenic effects of β2‐adrenergic receptor blockade in a mouse model of oxygen‐induced retinopathy

D Martini, MD Monte, C Ristori, E Cupisti… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 10.1111/j. 1471‐4159.2011. 07530. x Abstract Oxygen‐induced
retinopathy (OIR) is a model for human retinopathy of prematurity. In mice with OIR, beta …

Nanocarriers for the delivery of neuroprotective agents in the treatment of ocular neurodegenerative diseases

C Patel, S Pande, V Sagathia, K Ranch, J Beladiya… - Pharmaceutics, 2023 - mdpi.com
Retinal neurodegeneration is considered an early event in the pathogenesis of several
ocular diseases, such as diabetic retinopathy, age-related macular degeneration, and …